ID C5AVX0_METEA Unreviewed; 638 AA.
AC C5AVX0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000256|ARBA:ARBA00020585};
GN OrderedLocusNames=MexAM1_META1p3058 {ECO:0000313|EMBL:ACS40806.1};
OS Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB
OS 9133 / AM1) (Methylobacterium extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=272630 {ECO:0000313|EMBL:ACS40806.1, ECO:0000313|Proteomes:UP000009081};
RN [1] {ECO:0000313|EMBL:ACS40806.1, ECO:0000313|Proteomes:UP000009081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
RC {ECO:0000313|Proteomes:UP000009081};
RX PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA Lidstrom M.E.;
RT "Methylobacterium genome sequences: a reference blueprint to investigate
RT microbial metabolism of C1 compounds from natural and industrial sources.";
RL PLoS ONE 4:E5584-E5584(2009).
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis. {ECO:0000256|ARBA:ARBA00005001}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC subfamily. {ECO:0000256|ARBA:ARBA00009337}.
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DR EMBL; CP001510; ACS40806.1; -; Genomic_DNA.
DR AlphaFoldDB; C5AVX0; -.
DR STRING; 272630.MexAM1_META1p3058; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR KEGG; mea:Mex_1p3058; -.
DR eggNOG; COG2943; Bacteria.
DR HOGENOM; CLU_015730_1_0_5; -.
DR Proteomes; UP000009081; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd04191; Glucan_BSP_MdoH; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF5; GLUCANS BIOSYNTHESIS GLUCOSYLTRANSFERASE H; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009081};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACS40806.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..414
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 638 AA; 69017 MW; 07DCC6D928B71040 CRC64;
MPQAERSVEA GAGGGARPRG AGPAPRPASF RLRRLALAGP TLAIAAVIAA LALAAYGVPE
TWLGRAVLGL FVVLMAWQSF TAWQYLYGLI AALMGDRALS ALERRAATIS TRPTGLSRTA
AVVAIHAEDP LAVFSAIRVM ARSLQREGGD GSDIDIFVLS DTREGAISAV EEHEFARIQA
WRQREGRGMP RIRYRRRADN SGRKAGNIAE FCATYGHEYD FMIVLDADSL MTGAAMRRLA
RLMEENPRTG LIQTVSYAAG RDTLFARIQQ FAVRLYALLS LRCLETWQGP DGSYWGHNAI
LRIEAFANNA ELPILSGKPP LGGEILCHDI VEGALLRRAG WDVRLLPEMG GTWEEMPTNL
IDLLGRERRW CQGNLQHLRV LTMKGLLGAS RWHLGVGILG YCVYPLWIAF LGLGTWQAVR
SGELGLIGYG LDGGNAAAWA LATLVIAVMA LPKLLSIGYV LASARRRADF GGTRSLLVSA
ALEQAIWVLL WPVMALFAAG AVVTTLFGRV VRWDTQSRDD RSVPWREAFR LQSDAVAAGG
ALAVLLAFGN SWLALWMAPV ALALLTSPFQ SVLTSSTRLG LGSKARGLFL TEDDTRPAPE
LLELHQSRTA GAEPAAITAA PSPWLPVTID EASAPTLR
//
