ID C5B2M7_METEA Unreviewed; 2794 AA.
AC C5B2M7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE RecName: Full=Calx-beta domain-containing protein {ECO:0000259|SMART:SM00237};
GN OrderedLocusNames=MexAM1_META1p2085 {ECO:0000313|EMBL:ACS39882.1};
OS Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB
OS 9133 / AM1) (Methylobacterium extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=272630 {ECO:0000313|EMBL:ACS39882.1, ECO:0000313|Proteomes:UP000009081};
RN [1] {ECO:0000313|EMBL:ACS39882.1, ECO:0000313|Proteomes:UP000009081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
RC {ECO:0000313|Proteomes:UP000009081};
RX PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA Lidstrom M.E.;
RT "Methylobacterium genome sequences: a reference blueprint to investigate
RT microbial metabolism of C1 compounds from natural and industrial sources.";
RL PLoS ONE 4:E5584-E5584(2009).
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DR EMBL; CP001510; ACS39882.1; -; Genomic_DNA.
DR RefSeq; WP_012752748.1; NC_012808.1.
DR STRING; 272630.MexAM1_META1p2085; -.
DR KEGG; mea:Mex_1p2085; -.
DR eggNOG; COG0737; Bacteria.
DR eggNOG; COG1404; Bacteria.
DR eggNOG; COG2374; Bacteria.
DR eggNOG; COG2931; Bacteria.
DR eggNOG; COG3210; Bacteria.
DR eggNOG; COG3391; Bacteria.
DR eggNOG; COG3551; Bacteria.
DR eggNOG; COG5492; Bacteria.
DR HOGENOM; CLU_000765_0_0_5; -.
DR OrthoDB; 9803927at2; -.
DR Proteomes; UP000009081; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd10283; MnuA_DNase1-like; 1.
DR CDD; cd04486; YhcR_OBF_like; 1.
DR Gene3D; 2.60.40.1220; -; 1.
DR Gene3D; 2.60.40.2030; -; 2.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR008334; 5'-Nucleotdase_C.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR047971; ExeM-like.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR032812; SbsA_Ig.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR NCBIfam; NF038117; choice_anch_I; 1.
DR NCBIfam; NF033681; ExeM_NucH_DNase; 1.
DR PANTHER; PTHR42834; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210); 1.
DR PANTHER; PTHR42834:SF1; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210); 1.
DR Pfam; PF02872; 5_nucleotid_C; 1.
DR Pfam; PF13205; Big_5; 1.
DR Pfam; PF03160; Calx-beta; 2.
DR Pfam; PF00353; HemolysinCabind; 1.
DR SMART; SM00237; Calx_beta; 1.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF51120; beta-Roll; 1.
DR SUPFAM; SSF141072; CalX-like; 2.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009081};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 199..299
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT REGION 755..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2794 AA; 287579 MW; 764FD2C7A105E878 CRC64;
MATSLAAGDI AIVGYDADNP DDFAFVVLRD IEAGTAISFT DNGWSSSGNA LRTSEGTYTY
TAPTAVAAGT VVHPTSDGSA GGPDSPVYTA ALAPNFSFST DGDQILAYQG TAANPTFLYA
INFADGATGF AANGTNANTS ALPPGLVLGQ TAVALGADNG RYAGTLSGTR DGLLTAIGAA
GSWSQSDTVR IGAPGYSAFT ITAAPTIPAL SIDDIQVAEG DTGTRQLTFT VSLTAPAPSG
GVSFDIATAD GSATAGSDYV ARALTGQSIA AGQTATTFTV DLLGDTVIEP TETFTVTVSN
VRGATVADGQ GTGTLINDDT GPRIGGTAIF ESAPSLQGVS GATAPPVPTN ALQLVRLGAY
AATNDPATSA APNAEVVAYD SSTGRLYIQN TAENRIEITA LDATGALSKA GEILLSGLEQ
YGAVNSVAVF NGLVAVAYAN AAGDAPGRVA LFDANGTLLR SLTVGVGPDQ IVFTRDGSRI
LVANEGEQAS ATSNPVGGVS IIDVSGGAAN AAVMATVGFE GLDGSEATLR ARGLAIKPGN
GAAADIEPEY IAISPDDRFA YVTLQEVNGV AIIDLTNPGT APIAIQPLGS VNHSLAGNEF
DASDRDGPAN SQGVGTPSIR IAATPANAPI YGLLQPDAVA SFATGGATYF VTANEGDQRV
IGGGDDTGDV ARLSSIANSR LTPELQALKA DPAYARLNVL LRTGDTDGDG VIDQLHTLGG
RGISIFRQNL DGTITKVRET GGEFEKIFAQ IAPERFNNDQ VTGNTPDDRS DNKGPEPEGI
TIGTVNGRIY AFVGLERQSG VIVYDVTDPA NAAYVSYVPP RPGATTDLGP EVLTFIAADR
NPTGTPLLVS ANEVANGGAV VYAALPQGFT QEVAFSANSL AVSRAEGDTG ETVLTFTVER
SNGTLGAVTF TAEITGSGAN AADGADFAGA PALPLPVTGT IAAGAASAQV SVRVQADAVP
EADETFALTL RSASSNQPGI AAAVRPAAGT ATGTIVNDDA SLISAVQGAG AASPLVGRTV
TVEAIVVGDF QNGDADTKRN LGGFSLQEEA ADQDGNPLTS EGVFVFEGTG NRLVEVNEGD
RVRVTGTVTE FNGETQIAVS NAAAIQVVRA GGLTPAEVKA SAVAVELPAA GVIGTGTTAQ
PDLERYEGML VRFAQTLSIT EQFNLDRFNE IRLAAGGRTE TFTNEFEPNA AAYATYLAQT
AARSITYDDG LNTQNQPVEN LDGFGPVYAT ATAPRMGDTV TGLTGTLGFG PAGAYRVRAI
DDGDNRFVTA NPRPAEPDPV GGTLKVGSLN VLNYFTTLDT GSAARTAIGL EPRGANSPEE
LARQTEKLVT TLIGTGADVL GLTEIENQFR PGDPGNALEH LVGQLNLRAG AGTYASVNPG
AQLDQGQFLG GDAIAVGFIY KPSKVSVAMN TTIERLDDTD VAAFNPALLE RSTIGHLFNG
ANTSRAALAV TFNEIATGED FTAIITHFKS KGGTGTGADA DQGDGQGAWQ QQRELAATAL
AQWVSMRPTG TQDSDTLLLG DFNAYLKEDA LDILKAAGFT NLAEDRLANP YSYVFDGAYG
ALDHALASAS LNRQVTGVTE WHINADEADA IDYNLDFGRS PSSFDGRSPA RESDHDPVLV
GLRLDQTAPV LAASTPADDA ARVAVNADIV LRFSEAVRAG TGSITLSDGA GDLRTIATSD
TAQVAIAGDT VTINPSADLR PGTAYDVIVP AGAFTDAAGN ASAAIPQNRF DFTTEQAKPM
TYTLQILHAS DWEGGLLATQ RAANFAAIVD RLEDTTPNSI TLSTGDAWIP SPFYIAGADP
QMAATYNGVY NQFYGLSGAG AYGRLAASPG RADITIQNIV GVQAAVFGNH EFDGGPTEVA
NIIGANLGAA AGAADDTWLG AQFPYLSANL NLSREAALSG LVHRDGDLAA FAQTGPTSTQ
TGTGADKIAR STILVENGEK IAVIGATTQI NPLISTLGNV TVDGFTGRDE IALLASQINA
EVDRVLAANP GLNKVIVGTH LQQLANEQAL APLLRNVDVL IGGGSHTLLA DADDRLLSGD
RAGGGYPQFF TNASGQTLAL VNTASEYSYV GRLNVTFDDQ GHVIRDSINS ATSGAVAVDD
TTVTQLYGST AAAFTPGSKG FLVQQVIEGL DVNNDGIQET AGIADIIRQQ DGNILGRSSV
YLEGRRGEVR TEETNLGNLT ADANLWYAKQ FDGAVAVSIK NGGGIRDSIG SFSTTGGSTA
ELPPAANPAA GKAAGDISQL DVTNSLRFNN ALAMVTVTAS ELERVLEHAV SSAAPGATPG
AFPQIGGISF SFDATRQAQT VDVNGTVTRE GQRIISAAIV DADGFLIDTL VQDGQLVGDA
NRSIRAVTLD FLTTGTSTAP GLGGDNYPFP AYGENRVALS SAAPASLPNA ATFAAQGSEQ
DALAEYLKAF HSVTPFAQSD TAPAADARIQ NLAARSDSVL ARGVSRTGAD GHDVLQGTPF
ADRLFGGAGD DIIVNSAGND FLSGGRGNDT LVFNTSFASV TVTEAGSLTA ITGPDGRDLV
SGFERYLFSD ATIVVNDGQP LVDDLFYLSR NKDVFQAGQD ADAHYAQYGA REGRDPNAFF
STKGYLAANP EVRASGANPL DHYEQAGWKE GRDPGVRFDN EFYLAANPDV KAAGLNPLAH
YLAEGRAEGR AIHDAVGRSG DIRGGFDAEY YLLAHADVAQ AAGTTDTFAF AARHFEQYGW
QEGRNPNAVF DTKGYLAAYG DVKAAGLNPL THYDQYGWKE GRDPSADFDS STYLSTYTDV
AAAKIDPMQH FLQYGLYEGR STFADGTFGG GSLG
//
