ID   C5BWN7_BEUC1            Unreviewed;      1668 AA.
AC   C5BWN7;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=DEAD/H associated domain protein {ECO:0000313|EMBL:ACQ80703.1};
GN   OrderedLocusNames=Bcav_2453 {ECO:0000313|EMBL:ACQ80703.1};
OS   Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Beutenbergiaceae;
OC   Beutenbergia.
OX   NCBI_TaxID=471853 {ECO:0000313|EMBL:ACQ80703.1, ECO:0000313|Proteomes:UP000007962};
RN   [1] {ECO:0000313|EMBL:ACQ80703.1, ECO:0000313|Proteomes:UP000007962}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-8 / DSM 12333 / NBRC 16432
RC   {ECO:0000313|Proteomes:UP000007962};
RX   PubMed=21304633; DOI=10.4056/sigs.1162;
RA   Land M., Pukall R., Abt B., Goker M., Rohde M., Glavina Del Rio T.,
RA   Tice H., Copeland A., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D.,
RA   Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA   Pati A., Chen A., Palaniappan K., Hauser L., Chang Y.J., Jefferies C.C.,
RA   Saunders E., Brettin T., Detter J.C., Han C., Chain P., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA   Lapidus A.;
RT   "Complete genome sequence of Beutenbergia cavernae type strain (HKI
RT   0122).";
RL   Stand. Genomic Sci. 1:21-28(2009).
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DR   EMBL; CP001618; ACQ80703.1; -; Genomic_DNA.
DR   RefSeq; WP_015882943.1; NC_012669.1.
DR   STRING; 471853.Bcav_2453; -.
DR   KEGG; bcv:Bcav_2453; -.
DR   eggNOG; COG1201; Bacteria.
DR   HOGENOM; CLU_002025_3_0_11; -.
DR   OrthoDB; 9815222at2; -.
DR   Proteomes; UP000007962; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007962}.
FT   DOMAIN          65..257
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          321..537
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          363..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1168..1190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1386..1408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..382
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1668 AA;  174543 MW;  0CF781D7C0AA08DE CRC64;
     MRTRQDTGAG GVGTPAADAA GGGLSAGGAG AAPPAHPALA AFSEPTRTWF AESFPAPTEA
     QAGAWEAIAG GDHALVVAPT GSGKTLAAFL WALDALLGAE APDDAERCRV LYISPLKALA
     ADVERNLRSP LVGISRIAAR QGHPVRDVRV GMRTGDTPAG ERRRFATKPT DILITTPESL
     FLVLTSAARA GLAGVTTVIL DEVHALAGSK RGAHLALSLE RLDAMLPRPA QRIGLSATVR
     PVEEVGRFLA GARTIGDGGR SVRTVQPPSH KEIRIDVEVP VPDLEDLGDA ERELDLSGDA
     AGLLPDARPR TASVWPHVTE RVVDIISAHR TTLVFTNSRR GAERLTARIN EAWAERRLAV
     EGAIADDGDG DGDGDPGYDV DPSDDVEGAA PPADPGSAWG AQTPGQSGTA LAVAGDAVVA
     RAHHGSMSRE ERTRIEDDLK AGRLPAVVAT SSLELGIDMG SIDVVVQVGA PPSVASELQR
     IGRAGHQVGA VSHGVVLPTH RGDLLAAAVA AVRGREGAIE HLHIPANPLD VLAQQVVAML
     AMDDWKVAEL TALVRRAAPY AGLGDASLAA VLDMLAGRYP SEDFAELRPR IVWDRVDDVL
     SARPGALRLA ATSGGTIPDR GLYGVYLAAG AEDVATRGGR RVGELDEEMV YESRVGDTFT
     LGTSTWRIED ITPDRVLVSP AAGLPGRLPF WRGDAPGRPF ELGAALGAMV RDVERAREPA
     ELLTGWGLDE WARDNLLAYL TAQREATGHL STDHTIVVER FRDELGDWRL VIHTPFGARV
     HAPWALALAS RLQDRFGMDV QAMHADDGIV LRLPDAGGGD DDLGAVPLPG GWPDAAAADS
     AGPGTQVDLA DLLLDPDEVS GAVTAALAGS AHFAARFREA AARALLLPRR RPDRRQPLWQ
     QRHRAAQLLG VAARYPDFPI VLEAVRECLQ DDFDVPALAD LMRQVAAREI RVLEVTTTAP
     SPFARSLLFG YVGQFLYDGD APLAERRAAA LTLDPALLGE LLGEGLTDLA DLLDAGAVAD
     VEAQVGLLTE ASRVRDAEGA FDLVRRLGPV PAEEVARRAL DPEAVPGWLA DLERQRRIIA
     VRVAGREQWS AAEDAGRLRD ALGTALPLGL PAAVLESVPD PFGDLVRRHA RTHGPFTAAE
     VAHRFGLAPG AVLPVLRTFE RDGTLTAGRL RPAASGASAG SDGVPEPGAR EEFCDSEVLR
     RIRRRSLAAL RADVEAVPPA TLGVFLPRWQ QLGTLRGTDG VLAAVDQLAG ARLPSSALET
     TVLPARVRDY APAMLDELTS AGEVVWVGTG GSPGGGPSDG TIVLVPTDAA AVLAPLPGEL
     PTELARRVVE VLADGGRFFR DLYAAIASAA DGEPPAVAEV HDALWDAVWA GHVTNDTLAP
     LRARLEQRPS TSSRRAAAAR SPRSRSALSR RALMTPALAA AGSTAAQAAR IPTPASAAGR
     WSVVGAVETD PTIRLAATAA ALLDRHGVLV RGAVAAEEVP GGFGALYRVL VRLEESGQVR
     RGYVVEGLGA SQFALPECID RLRADAAANP GPVLLAAVDP ANPYGAALPW PAAPTSAEGV
     TTGARPRRVP GAHVVLVDGA LVLYLERGAR TLLSFTADDA RLRAAAAALA NAAASGALGR
     VVVQRSDGAA TLVADTPLRQ ALLDAGFVAT PRGLRVRQVR NGAARARG
//