ID C5C415_BEUC1 Unreviewed; 429 AA.
AC C5C415;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=ROK family protein {ECO:0000313|EMBL:ACQ79928.1};
GN OrderedLocusNames=Bcav_1672 {ECO:0000313|EMBL:ACQ79928.1};
OS Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Beutenbergiaceae;
OC Beutenbergia.
OX NCBI_TaxID=471853 {ECO:0000313|EMBL:ACQ79928.1, ECO:0000313|Proteomes:UP000007962};
RN [1] {ECO:0000313|EMBL:ACQ79928.1, ECO:0000313|Proteomes:UP000007962}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-8 / DSM 12333 / NBRC 16432
RC {ECO:0000313|Proteomes:UP000007962};
RX PubMed=21304633; DOI=10.4056/sigs.1162;
RA Land M., Pukall R., Abt B., Goker M., Rohde M., Glavina Del Rio T.,
RA Tice H., Copeland A., Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Hauser L., Chang Y.J., Jefferies C.C.,
RA Saunders E., Brettin T., Detter J.C., Han C., Chain P., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Lapidus A.;
RT "Complete genome sequence of Beutenbergia cavernae type strain (HKI
RT 0122).";
RL Stand. Genomic Sci. 1:21-28(2009).
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; CP001618; ACQ79928.1; -; Genomic_DNA.
DR AlphaFoldDB; C5C415; -.
DR STRING; 471853.Bcav_1672; -.
DR KEGG; bcv:Bcav_1672; -.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_3_11; -.
DR Proteomes; UP000007962; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007962}.
FT DOMAIN 46..87
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|Pfam:PF09339"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 44801 MW; ADBB23D236C43A75 CRC64;
MVSETDRPTG ATWQGGPPGS GTDAVGHARG PWPVAMPATS YGALVSFIRS RPGLTRHQLL
AATGMSRTTL FERLEALFQH GYVYQDGSAP PGSGTRGPGR RSELLRWDTR GRVVLVLDLG
QTHARLCVTG VDGRILRMRD VAVEIDTDAP AYLAELFRIS HELVEAGEDE TLIGVALGIP
GPVDPATGIL GTSTTMPRWE RFPVLDSIRD HWQVPAVIEN DARAFALGES SVIGADRTVL
AVKYATGIGA GIVDAGHVLE GADGAAGDIG HVRITDDGPV CTCGRRGCLA AWASGHALLR
RLADTGVRNL RDIVERVAAG DPAVCAAVDD ATARLSRVLA TVVAAANPDD LVLGGALGRI
PRVVSRIDAS IRQDVTERAR HHLTVSAAHL GADGAVVGLS RKVVDLVYDP AVIDAAILGQ
TGAGTATPA
//
