ID C5C9H4_MICLC Unreviewed; 527 AA.
AC C5C9H4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta) {ECO:0000313|EMBL:ACS30126.1};
DE SubName: Full=Probable propionyl-CoA carboxylase beta chain 5 {ECO:0000313|EMBL:SQG49080.1};
DE EC=6.4.1.3 {ECO:0000313|EMBL:ACS30126.1, ECO:0000313|EMBL:SQG49080.1};
GN Name=accD5 {ECO:0000313|EMBL:SQG49080.1};
GN OrderedLocusNames=Mlut_05890 {ECO:0000313|EMBL:ACS30126.1};
GN ORFNames=NCTC2665_01611 {ECO:0000313|EMBL:SQG49080.1};
OS Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 /
OS NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Micrococcus.
OX NCBI_TaxID=465515 {ECO:0000313|EMBL:ACS30126.1, ECO:0000313|Proteomes:UP000000738};
RN [1] {ECO:0000313|EMBL:ACS30126.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NCTC 2665 {ECO:0000313|EMBL:ACS30126.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Lowry S., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Young M., Greenblatt C.;
RT "Complete sequence of Micrococcus luteus NCTC 2665.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000000738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 /
RC NCTC 2665 / VKM Ac-2230 {ECO:0000313|Proteomes:UP000000738};
RX PubMed=19948807; DOI=10.1128/JB.01254-09;
RA Young M., Artsatbanov V., Beller H.R., Chandra G., Chater K.F., Dover L.G.,
RA Goh E.B., Kahan T., Kaprelyants A.S., Kyrpides N., Lapidus A., Lowry S.R.,
RA Lykidis A., Mahillon J., Markowitz V., Mavromatis K., Mukamolova G.V.,
RA Oren A., Rokem J.S., Smith M.C., Young D.I., Greenblatt C.L.;
RT "Genome sequence of the Fleming strain of Micrococcus luteus, a simple
RT free-living actinobacterium.";
RL J. Bacteriol. 192:841-860(2010).
RN [3] {ECO:0000313|EMBL:SQG49080.1, ECO:0000313|Proteomes:UP000248985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC2665 {ECO:0000313|EMBL:SQG49080.1,
RC ECO:0000313|Proteomes:UP000248985};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001628; ACS30126.1; -; Genomic_DNA.
DR EMBL; LS483396; SQG49080.1; -; Genomic_DNA.
DR RefSeq; WP_012750767.1; NZ_WBMF01000012.1.
DR AlphaFoldDB; C5C9H4; -.
DR STRING; 465515.Mlut_05890; -.
DR EnsemblBacteria; ACS30126; ACS30126; Mlut_05890.
DR KEGG; mlu:Mlut_05890; -.
DR PATRIC; fig|465515.4.peg.558; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_018822_6_2_11; -.
DR Proteomes; UP000000738; Chromosome.
DR Proteomes; UP000248985; Chromosome 1.
DR GO; GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
DR GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
DR GO; GO:0004658; F:propionyl-CoA carboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR000438; Acetyl_CoA_COase_Trfase_b_su.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR PRINTS; PR01070; ACCCTRFRASEB.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ACS30126.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000738}.
FT DOMAIN 9..265
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 273..521
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 527 AA; 56054 MW; 6C09837A0E48E549 CRC64;
MTDPDLTTTA GRLADLHRRL EATAAPGGPD AVERQHARGK HTARERIDLL LDEGSFVELD
ALAVHRTTAF GMDAKHPAGD GLVSGFGTVD GRQVAVYSQD FTVFGGSLSE RNGQKIVKVQ
EFAARNGCPV IGILDGGGAR IQEGVASLAQ FADIFRNNVL ASGMIPQISL IMGPSAGGAA
YSPALTDVVV MVDQTSHMFI TGPDVIKTVT GEDVDMETLG GARSHNATSG TAHYMASSEE
DAIAYVQDLL EFLPSNNLAE APAFEPTSLD LTAEDEALDV IVPDSAHQPY DMLEVIASIV
DEGHLLQLQE LYAPNVITGL ARLDGMSVGV VANQPMQFAG TLDIAASEKA ARFVRFCDAF
NIPIITLVDV PGFLPGTDQE FNGIIRRGAK LIYAYAEATV PKLTVITRKA FGGAYIVMGS
KKLGADLNLA WPSAQIGVMG AQGAVNILYR RDLKATAEAG GDVDARRAEI VADYEAELLN
PYQAAELGYV DAVVPPHATR GHLVRALRAT YHKREARPAK KHGNMPL
//
