ID C5DLV1_LACTC Unreviewed; 709 AA.
AC C5DLV1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 03-MAY-2023, entry version 60.
DE SubName: Full=KLTH0G03762p {ECO:0000313|EMBL:CAR24762.1};
GN OrderedLocusNames=KLTH0G03762g {ECO:0000313|EMBL:CAR24762.1};
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR24762.1, ECO:0000313|Proteomes:UP000002036};
RN [1] {ECO:0000313|EMBL:CAR24762.1, ECO:0000313|Proteomes:UP000002036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC {ECO:0000313|Proteomes:UP000002036};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase beta subunit
CC family. {ECO:0000256|ARBA:ARBA00010926}.
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DR EMBL; CU928171; CAR24762.1; -; Genomic_DNA.
DR RefSeq; XP_002555199.1; XM_002555153.1.
DR AlphaFoldDB; C5DLV1; -.
DR STRING; 559295.C5DLV1; -.
DR GeneID; 8293465; -.
DR KEGG; lth:KLTH0G03762g; -.
DR eggNOG; KOG1616; Eukaryota.
DR HOGENOM; CLU_011585_0_0_1; -.
DR InParanoid; C5DLV1; -.
DR OMA; INHIIPH; -.
DR OrthoDB; 120305at2759; -.
DR Proteomes; UP000002036; Chromosome G.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd02859; E_set_AMPKbeta_like_N; 1.
DR Gene3D; 6.20.250.60; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR032640; AMPK1_CBM.
DR InterPro; IPR006828; ASC_dom.
DR InterPro; IPR037256; ASC_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR10343; 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT; 1.
DR PANTHER; PTHR10343:SF87; SNF1 PROTEIN KINASE SUBUNIT BETA-1; 1.
DR Pfam; PF16561; AMPK1_CBM; 1.
DR Pfam; PF04739; AMPKBI; 1.
DR SMART; SM01010; AMPKBI; 1.
DR SUPFAM; SSF160219; AMPKBI-like; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002036}.
FT DOMAIN 584..700
FT /note="Association with the SNF1 complex (ASC)"
FT /evidence="ECO:0000259|SMART:SM01010"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..155
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 709 AA; 78273 MW; 279E61CB4C40E48D CRC64;
MGNNPSTANM QNKRVSQLAQ EPRGRQDSIT SQLFPSRTSG RNPESKVGWK SRVLHGNRPS
ASPASTPPVQ SPFRKNYTLE VTTESAPYNL KKSISGNPAP PMCTTTHASA DESSSSSLRD
HLAELSLQNS ESQPNRKTSP GLGPAPAPAP VLRSPGPSTP VVKYTKHDAI SDQISSITSL
KKMLVEGRVG DNIHPPPTSI DIPRRPSAAL SDAYFSDDGD DEESLLQGTN DVVINNSVLE
NAMKRKRGTK KNKGVGASSE SHEHISYPGL KKLKPLEHGG DKRDLPHFRA MHPRPSEDNV
GPDSAAIPRL ITDSLNRIDS FEKGTVEHYE GANESGFSSQ NLTSSDMRDS DDADEDRGPG
THVILNWKDN IVDPKTCKMS IVSKDISSTL NPHKKFSKIP MVFDMERNCW TAHDLYLPSG
VYKFQFLING ELRHSDYLPT ATDSFGNCVN WFEVVEGHDS IEPSRDVISS EDVKLSKDQI
AVEQPAPERP ALGSDGSSSS NWKGSSRHVE RSGTPFSDYT GLCSRSELTK PELRHNNTSS
YDLLAPVPRP KYEYTDEIPE LFKANFDGSL VPPPYEEREL TKDGSQKPPS FLHRVQDCNQ
DVLFADLQQN GQIDSQAAEE AFLQQYPTPD LPVYLDSSFL NAVFSGFQDK TDSKTRVNHI
VPHVNLNHLL TSSIRDEIIS VGCTTRYEGK FITQIIYTPC YYSNKDGAH
//
