ID   C5DMT2_LACTC            Unreviewed;       897 AA.
AC   C5DMT2;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=Exocyst complex component SEC5 {ECO:0000256|RuleBase:RU365069};
GN   OrderedLocusNames=KLTH0G11418g {ECO:0000313|EMBL:CAR25093.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR25093.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR25093.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC       exocytic vesicles with fusion sites on the plasma membrane.
CC       {ECO:0000256|RuleBase:RU365069}.
CC   -!- SUBUNIT: Component of the exocyst complex.
CC       {ECO:0000256|RuleBase:RU365069}.
CC   -!- SIMILARITY: Belongs to the SEC5 family. {ECO:0000256|ARBA:ARBA00010578,
CC       ECO:0000256|RuleBase:RU365069}.
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DR   EMBL; CU928171; CAR25093.1; -; Genomic_DNA.
DR   RefSeq; XP_002555530.1; XM_002555484.1.
DR   AlphaFoldDB; C5DMT2; -.
DR   STRING; 559295.C5DMT2; -.
DR   GeneID; 8293809; -.
DR   KEGG; lth:KLTH0G11418g; -.
DR   eggNOG; KOG2347; Eukaryota.
DR   HOGENOM; CLU_339546_0_0_1; -.
DR   InParanoid; C5DMT2; -.
DR   OMA; WAARHAN; -.
DR   OrthoDB; 1972109at2759; -.
DR   Proteomes; UP000002036; Chromosome G.
DR   GO; GO:0000145; C:exocyst; IEA:UniProtKB-UniRule.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR029175; EXOC2/Sec5.
DR   InterPro; IPR039481; EXOC2/Sec5_N_dom.
DR   PANTHER; PTHR13043:SF1; EXOCYST COMPLEX COMPONENT 2; 1.
DR   PANTHER; PTHR13043; EXOCYST COMPLEX COMPONENT SEC5; 1.
DR   Pfam; PF15469; Sec5; 1.
PE   3: Inferred from homology;
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365069};
KW   Protein transport {ECO:0000256|RuleBase:RU365069};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365069}.
FT   DOMAIN          78..896
FT                   /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15469"
SQ   SEQUENCE   897 AA;  103381 MW;  139F290B5443DDCE CRC64;
     MGDSAFTFGA RELCDFYQLK DLDPKVSWAE DSSVVYSLSQ PQNADSIDSS YVVLNELLRQ
     EHEHSTERND TIETAGLSDP LNSSTRLEDL LDHYRIPQDE RYKYYINSKK FNSKLYLKQL
     HAQDSFKDLS LSLDHLDQSL QAQSEDLKQL VQRNFVKYVR SKNNLDRIYE QFNKFSLGES
     RDFGTDDLGE TVDESIREIT IKVKPILDIS TKRRNAQTTI AFLQDHKQFF DAPKKLKHCL
     IEKDFANLVV EYNNAHSTFK DLQRRGFTFP ILTKIWDDIE NTICHYREVI WDSLVNLVAG
     ETQEQILPLI SKLLDLNYAG NPIIEWINTK LDIFERKIGE VCSQMFTKII QSQKKIVESA
     LNEKVDLTFY LSIKNLADKL NDGQVSRFGI VGSSFLKNPG LCDTVVVVEM WLLISKFINL
     LSKESSDFVE FWGHVEKFLD GTYQTSLMND KRKDDILGSN TQTRDDYGQF LEMKNEQIRC
     IRRRGEDFLK RLCENLSNFF NASQDTLSTG SIPEKETGIP LDYGFLPPNS NCLSCLRYLP
     RIVEPILKFT TELAQLNVSS SSIEFLRETN ALVLERSISA ISATKLRDIS SFHTLEDWSM
     YRTSGSEEYG ITQFPEVVQT FQNLSITTVR NMLYSYEKLP VLNGIYVVTH PSRKMLAGIE
     VQQIVSMEAV LESILKEAAK EKENPRNPRT ILTLTNLQYI KGSVFPQVLR YFDESFETQL
     SRKNLEIFTL LAKMETSILG NYLSDLKVTL RDILEERFYE INWAAYNSNS FRVGDYIIEA
     LMVLVRVHSE CFKIAPQLIG RILRESQVFI SKYLFEAFKP YAGNLSSDGL LQVVVDLQFF
     LRVLSNMLET TTEATINATL QNCFENDLDR MQRCIKETEP IVSANLEKTS VQFASFK
//