ID C5DTV3_ZYGRC Unreviewed; 2406 AA.
AC C5DTV3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 69.
DE SubName: Full=ZYRO0C11572p {ECO:0000313|EMBL:CAR27214.1};
GN OrderedLocusNames=ZYRO0C11572g {ECO:0000313|EMBL:CAR27214.1};
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307 {ECO:0000313|EMBL:CAR27214.1, ECO:0000313|Proteomes:UP000008536};
RN [1] {ECO:0000313|Proteomes:UP000008536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229 {ECO:0000313|Proteomes:UP000008536};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
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DR EMBL; CU928175; CAR27214.1; -; Genomic_DNA.
DR RefSeq; XP_002496147.1; XM_002496102.1.
DR STRING; 559307.C5DTV3; -.
DR GeneID; 8203365; -.
DR KEGG; zro:ZYRO0C11572g; -.
DR HOGENOM; CLU_000380_3_0_1; -.
DR InParanoid; C5DTV3; -.
DR Proteomes; UP000008536; Chromosome C.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0030623; F:U5 snRNA binding; IEA:InterPro.
DR GO; GO:0017070; F:U6 snRNA binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd08056; MPN_PRP8; 1.
DR CDD; cd13838; RNase_H_like_Prp8_IV; 1.
DR Gene3D; 1.20.80.40; -; 1.
DR Gene3D; 3.30.420.230; -; 1.
DR Gene3D; 3.90.1570.40; -; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 3.30.43.40; Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain; 1.
DR InterPro; IPR000555; JAMM/MPN+_dom.
DR InterPro; IPR012591; PRO8NT.
DR InterPro; IPR012592; PROCN.
DR InterPro; IPR012984; PROCT.
DR InterPro; IPR027652; PRP8.
DR InterPro; IPR021983; PRP8_domainIV.
DR InterPro; IPR043173; Prp8_domainIV_fingers.
DR InterPro; IPR043172; Prp8_domainIV_palm.
DR InterPro; IPR019581; Prp8_U5-snRNA-bd.
DR InterPro; IPR042516; Prp8_U5-snRNA-bd_sf.
DR InterPro; IPR019580; Prp8_U6-snRNA-bd.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR019582; RRM_spliceosomal_PrP8.
DR PANTHER; PTHR11140; PRE-MRNA SPLICING FACTOR PRP8; 1.
DR PANTHER; PTHR11140:SF0; PRE-MRNA-PROCESSING-SPLICING FACTOR 8; 1.
DR Pfam; PF08082; PRO8NT; 1.
DR Pfam; PF08083; PROCN; 1.
DR Pfam; PF08084; PROCT; 1.
DR Pfam; PF12134; PRP8_domainIV; 1.
DR Pfam; PF10598; RRM_4; 1.
DR Pfam; PF10597; U5_2-snRNA_bdg; 1.
DR Pfam; PF10596; U6-snRNA_bdg; 1.
DR SMART; SM00232; JAB_MPN; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008536};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 2171..2303
FT /note="JAB1/MPN/MOV34 metalloenzyme"
FT /evidence="ECO:0000259|SMART:SM00232"
FT REGION 1..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..75
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2406 AA; 278469 MW; 875735A8FBA5545B CRC64;
MNNSDSPPPP PPPPELFEPD GMELPPPPPP PLDDNDDNML PPPPPPGLDD DADFMEQPPP
PPSPSMPPPL PPPTINDGND KMNNLDNVLN GKLPNGMKRK LEDGKVSKVS RKKLKKLKKS
GRGQVQAQKP ELPPEHLRKI IESHTDMTSK RFNHEKRAFL GALKYMPHAI LKLLENMPQP
WEQVKTVKVL YHATGAITFV NEIPRVIEPV YIAQWSTMWL AMRREKRDRT HFKRMRFPPF
DDDEPPVSYS DNIQTLEPPN PIYLQLDNYE DKLVKEWLYD SKPLINNQGK VNGTSYKTWY
LSPQIMANLN RLSTPLKSEI HDDNHYYLFD KKSFFTSKAL NNAIPGGPKF EPLYPHEEEE
DYNEFNSIDR IIFRVQIRSE YRIAFPHLYN SRPRSVQMSW YSKPICCLPN REEDPDLPTF
SFDVMFNPIT RTQNKKNQRS DNDEFTLNED FTALMTNEEL ELPETKDAFD LYHSPYPFNK
NSGRMVRAQD VTLVKNWYLQ RSDQDFPLKT RVSYQRLLKS HVFNELKTKK PADVKKVKLL
KSLRNTKYFQ QTTIDWVEAG LQLCRQGHNM LNLLIHRKGL TYLHLDYNFN LKPTKTLTTK
ERKKSRFGNA FHLMREILKM IKLLVDAHVQ FRLGNVDAFQ LADAIYYIFN HLGHLTGIYR
YKYKVMHQIR ACKDLKHVVY HRFNKIIGKG PGCGFWQPAW RVWIFFMRGI IPLLERWLGN
LLVRQFEGRN NEIIKTTTKQ RADAYFDLEL RASVMKDILE MIPEGIRQDK ARTILQHLSE
AWRCWKANIP WDVPGMPIPV KKIIERYVKA KADGWVSGAH SNRERIKKGT HVEKTALKKN
LGRMTRLWIK YEQERQQQIE KNGPEITPDE ATAIFSTMVD WLEKRDFSPI PFPPLAYKND
TKILVLTLEN LKDAYGSKVR LNSAEREELA LIEAAYDNPH ETLNRIKKYL LTQRVFKPVE
LSMVDHYQNI APVYTVDPLE KLTDLYLDQY LWYEADERKL FPNWIKPSDS EIPPLLTYKW
CQGVNNLSEV WDVSKGQSTV MMETKLEEMA EKIDFTLLNR LLRLIVDPNI ADYMTAKNNV
ILNYKDMSHV NKYGLIRGLQ FSSFIYQYYG LMMDILMLGI DRAMDFAGPP NDPNDFLQLK
HPSVEKKQPI KLYARYLDTV YVLFHFEEEE ANELTDDYLS ENPDPNFSNA VGYNNKRCWP
RDARMRLVRE DVNLGRAVFW EMQGRVPASL TKIKWDNSFV SIYSKNNPNL LFSMCGFEVR
ILPKQRTNEV ISTGEGVWDL IDERTKQRTA KAFLKVSQEE IERFDSKIRG ILMGSGSTTF
SKVASKWNTA LLSLFTYFRE AIVATEPLLD ILVKSETKIQ NRVKLGLNSK MPTRFPPAVF
YTPKELGGLG MLSASHILIP AADRTYSRQT DTGITHFRAG MTHDDDKLIP TIFRYITTWE
NEFLDSQRVW AEYATKRQEA IQENRRIAFE ELESSWDRGI PRISTLFQRD RHTLAYDRGH
RIRREFKQFS LERNSPFWWT NAHHDGKLWN LNAYRTDVIQ ALGGIETILE HTLFKGTGFS
SWEGLFWEKA AGFEDSMQFK KLTHAQRTGL SQIPNRRFTL WWSPTINRAN VYVGFLVQLD
LTGIFLHGKI PTLKISLIQI FRAHLWQKIH ESIVFDLCQI LDGQLDVLQI ESVNKEAVHP
RKSYKMNSSA ADITVNSIHQ WEVCKPSLLH ATNDNFKAAL TDKMWVDVQL RYGDYDSHDI
SRYVRAKFLD YTTDSVSMYP SPTGVMVGID LAYNMYDVYG NWFNGLKPLM QNSMRTIMRA
NPALYVLRER IRKGLQIYQS NVQEPFLNSS NYAELFNNDT KLFVDDTNVY RVTVHKTFEG
NVATKAINGC IFTLNPKTGH LFLKIIHTSV WAGQKRLSQL AKWKTAEEVS ALVRSLPKEE
QPKQIIVTRK AMLDPLEVHM LDFPNISIRP TELRLPFAAS MAIDKLSDTV LKATEPQMLL
FNIYDDWLER VSSYTAFSRI ILLLRGLKTN EEKAKMILLG DPTIPIKSHH LWPSFTDEQW
IEVESKMRDL ILEEYSKKYN VNISSLTQTE IKDLILGQDV KAPSVRRQKM AELEAAKNDS
TRDDELETGA STVMKTKTVN AQGEEIVVVT SANYENQAFS SKNEWRKNAI ANSLLYLRLR
NIYIASEDFI EEKPVFVLPR NLLKKLVEIS DVKIQVAAYL YGSSPADHPN IKEIKTIALI
PQLGNSKAVQ LGKIPNGDTN PQLDGLELLG WIHTQTEDIK FMTAFDVATH ADLFSSVKRE
AIDLTVCLAQ GSVSLAAYNL TDEGYSWGIQ NKDVITTTPE EFDPSYSEHA QLLLSERIMG
NFLVPSTDVW NFTFSGATFD PSLDYELKVG IPLEFYNEMH RVIHFMQFNE LAGDEALEAE
QEDVLA
//
