ID C5E2U3_LACTC Unreviewed; 402 AA.
AC C5E2U3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=KLTH0H07744p {ECO:0000313|EMBL:CAR30354.1};
GN OrderedLocusNames=KLTH0H07744g {ECO:0000313|EMBL:CAR30354.1};
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR30354.1, ECO:0000313|Proteomes:UP000002036};
RN [1] {ECO:0000313|EMBL:CAR30354.1, ECO:0000313|Proteomes:UP000002036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC {ECO:0000313|Proteomes:UP000002036};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SIMILARITY: Belongs to the DDI1 family.
CC {ECO:0000256|ARBA:ARBA00009136}.
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DR EMBL; CU928180; CAR30354.1; -; Genomic_DNA.
DR RefSeq; XP_002556216.1; XM_002556170.1.
DR AlphaFoldDB; C5E2U3; -.
DR STRING; 559295.C5E2U3; -.
DR MEROPS; A28.001; -.
DR GeneID; 8294534; -.
DR KEGG; lth:KLTH0H07744g; -.
DR eggNOG; KOG0012; Eukaryota.
DR HOGENOM; CLU_020435_2_0_1; -.
DR InParanoid; C5E2U3; -.
DR OMA; EQPMDIL; -.
DR OrthoDB; 1332686at2759; -.
DR Proteomes; UP000002036; Chromosome H.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05479; RP_DDI; 1.
DR CDD; cd14309; UBA_scDdi1_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR019103; Peptidase_aspartic_DDI1-type.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12917; ASPARTYL PROTEASE DDI-RELATED; 1.
DR PANTHER; PTHR12917:SF1; AT13091P; 1.
DR Pfam; PF09668; Asp_protease; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000002036}.
FT DOMAIN 363..402
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 333..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 44399 MW; 0A407CB3C55A2BAD CRC64;
MRLTINSEIT DEIFGPLDVT AEMSLQDLIA LLEFECGFDA TKHNLLHKAT ALNSSESKTL
QELQFENDEL LVIKAKINNV HENSQSGASM EDMLVEQARQ QILQNPALRA QIVSSNPGFE
SIINDATAFR QQAGPHLLQS MQGGSRQNPF GIAQTEYDEL MRNPDDPANQ KRIGELISQQ
EIDEQMRNAL EFTPEAFTTV HMLYVNLEIN GYPVKAFVDS GAQSTIISTK LAEKAGLSRL
IDKRFSGEAH GVGVQKIIGK IHIAQVKIET QHVPCSFTVL DTHVDMLLGL DMLKRHQACI
DLKDNVLRIA GVQTRFLSEA EIPESLEAKI SESTSQGLNI PAPSAQLEPP KKAQTSQPHP
ERAFPESVVQ QLMDLGFSRS EVLRSLEQAN GNPDVAAALL FQ
//
