ID C5FIE0_ARTOC Unreviewed; 1571 AA.
AC C5FIE0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Myosin-2 {ECO:0000313|EMBL:EEQ29120.1};
GN ORFNames=MCYG_01939 {ECO:0000313|EMBL:EEQ29120.1};
OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ29120.1, ECO:0000313|Proteomes:UP000002035};
RN [1] {ECO:0000313|Proteomes:UP000002035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DS995702; EEQ29120.1; -; Genomic_DNA.
DR RefSeq; XP_002849005.1; XM_002848959.1.
DR STRING; 554155.C5FIE0; -.
DR GeneID; 9229057; -.
DR VEuPathDB; FungiDB:MCYG_01939; -.
DR eggNOG; KOG0160; Eukaryota.
DR HOGENOM; CLU_000192_3_1_1; -.
DR OMA; EIMFDDR; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000002035; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd15480; fMyo2p_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR046943; Fungal_Myo2/2A_CBD.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF706; MYOSIN-11; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002035}.
FT DOMAIN 6..59
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 74..780
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1231..1500
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 655..677
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 915..1078
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1571 AA; 179031 MW; 206F8445D1AD9BDB CRC64;
MVHTYEVGTR AWQPDPTEGW IASEVTEKVV DGEKVKLVFT LENGETKTTE TTLAELASDT
GEKLPPLMNP TMLEASEDLT NLSHLNEPAV LQAIKLRYYQ KEIYTYSGIV LIATNPFARV
DSLYVPQMVQ VYAGKQRASQ APHLFAIAEE AFADMLRDTQ NQTIVVSGES GAGKTVSAKY
IMRYFATRET SDNPGSYSTG RADSISETEE QILATNPVME AFGNAKTTRN DNSSRFGKYI
EILFDNRTNI IGAKIRTYLL ERSRLVFQPL KERNYHIFYQ LIAGATDAER QELGLLAVEE
FDYLNQGGTP VIDGVDDKAE LEATRKSLTT IGLDDEIQAS IFKILAALLH LGNVKIVATR
NDSSLEPTEP SLVRTCEMLG IDATEFAKWT VKKQLVTRGE KIISNLNQAQ ALVVRDSVAK
FIYSSLFDWL VETINRSLAT EEVLSRATSF IGVLDIYGFE HFAKNSFEQF CINYANEKLQ
QEFNQHVFKL EQEEYVREQI DWTFINFSDN QPCIDLIEGK LGILALLDEE SRLPMGADEQ
FVNKLHHNFA ADKQKFYKKP RFGKSSFTVC HYAIDVTYES DGFIEKNRDT VPDEHMEVLR
NSSNTFIRDV LQAASAIREK DSASMSSRPV AAPGRKIGVA VNRKPTLGGI FKSSLIELMN
TINSTDVHYI RCIKPNEAKE AWKFEGPMVL SQLRACGVLE TVRISCAGYP TRWTYEEFAL
RYYMLCHSSQ WTSEIRAMCH AILSKALGDI TQQQQDKYQL GLTKIFFRAG MLAFLENLRT
SRLNECAIMI QKNLKCKYYR RKYLAMRDSI LAFQGLIRGF LARQHAEGAR QVKAATTIQR
VWRGQKDRKY YHRIRNNVIL VESLARGYLC RRNIMDSILG NAAKVIQRSF RTWRQLRKWR
DYRRKVVIVQ NLWRGKKARR QYKTLREEAR DLKQISYKLE NKVVELTQSL GSLKQQNKSL
TSQLENYDGQ IKSWRSRHNA LEARSRELQA EANQAGITAA RLTAMEEEMS KLQLNHNESL
ATVKKLQEEE RSTRETLRLT SLELDNAKNA IAVHEQEKTY LRQQVVELQD ELEFAKRSAP
LNGLNGDLNG GPTQPSLSGL INLVASKKPK PKRRSAGLEK VEIDRFSGAY NPRPVSMAIP
TGGVGRNDFR TSAFAPGIDS VEIELENLLS EEDELNDEVT MGLIKNLKIP LPSSDPPPTE
KEVLFPSYLI NLVTSEMWNN GFVKESERFL ANVMQAIQQE VMQHDSEDTI SAGAFWLSNV
HEMLSFVFLA EDWYEAQKTD NYEYDRLLEI VKHDLESLEF NIYHTWMKGL KKKLFKMIVP
AIIESQSLPG FVTSETNRFL GKLLPSNNNP AYSMDNLLSL LNNVFKAMKA YYLEDSIVTQ
AVTELLRLVG VTAFNDLLMR RNFLSWKRGL QINYNITRIE EWCKSHDMPE GTLQLEHLMQ
ATKLLQLKKA TLNDIEIIQD ICWMLSPNQI QKLLNQYLVA DYEQPINGEI MKAVASRVTE
KSDVLLLTAV DMEDSGPYEI AEPRAITALE TYTPSWLQTP RLKRLAEIVS LQAMAQQDRL
DSLEMGEPPE D
//
