ID C5FM19_ARTOC Unreviewed; 720 AA.
AC C5FM19;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Pre-rRNA-processing protein ESF1 {ECO:0000313|EMBL:EEQ30741.1};
GN ORFNames=MCYG_03560 {ECO:0000313|EMBL:EEQ30741.1};
OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ30741.1, ECO:0000313|Proteomes:UP000002035};
RN [1] {ECO:0000313|Proteomes:UP000002035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS995703; EEQ30741.1; -; Genomic_DNA.
DR RefSeq; XP_002848054.1; XM_002848008.1.
DR AlphaFoldDB; C5FM19; -.
DR STRING; 554155.C5FM19; -.
DR GeneID; 9229376; -.
DR VEuPathDB; FungiDB:MCYG_03560; -.
DR eggNOG; KOG2318; Eukaryota.
DR HOGENOM; CLU_010564_0_1_1; -.
DR OMA; YEMEMSW; -.
DR OrthoDB; 131620at2759; -.
DR Proteomes; UP000002035; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002035}.
FT DOMAIN 633..660
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..113
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..159
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..532
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..688
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 81907 MW; 5AEF77FDE2EC4AE0 CRC64;
MGEKMASKKK KARSSGQSSA NVISDPRFAN IQSDPRYRLP SKKHTHVKLD KRFSHMLRDS
DFSKNAPVDR YGRKLARDDT RKQLEKFYRF DEDDEDKDEQ DEYLEEGYLS IDDDDEVQKE
LQRVERVGYD PARDGGFESS SSDESSSDEE EDEDADNIGE ELPGPGQQDT DIPTGDYTER
IAVVNLDWDN IKAQDLMAVF TSFLPAGGAI RKVSIYPSEF GRERMEMEEM DGPPKEIFSQ
NTKGEDEDSL SEEEDEEEVE EKIKNSLLVE GNGDDFDAGK LRQYQLERLR YFYAILTCSS
REVAKHIYDA VDGTEYMSSA NFFDLRFVPD STDFTDDVPR DECTRLPDGY QPSDFVTDAL
QHSKVKLTWD ADDRARKEAQ ERAFKGSRKE IDENDLKAYL GSDSSEDEAE AADVMETGAT
QKLSKKEAER ARVRALLGLS DKPEAGKKEA KPVGEMEVTF SAGLSAAPAK ETVFANEPEK
EETTREKYVR KERERKQRRK ARLKASRSGE GTHEGENDNK TGETKGAEED LGFDDPFFTA
PELDAANAAK QRKEEKRKQQ EQRRAEEEAS ASKRAELELL MMDDDKAAPI AHFDMNEIEK
AEKRSRKSGK HKRGKKDTTE AEPVDNFEVN VKDPRFQSLF ESHEYAIDPT NPRFKQTKGM
NTLLEEGRKR RRHIDDAERS DEKAGHKQKK NKQSKSSSAV ADDGEAVSKL VEKVKAKTKK
//
