ID C5FPZ1_ARTOC Unreviewed; 1536 AA.
AC C5FPZ1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Translation initiation factor eIF4G {ECO:0000313|EMBL:EEQ31944.1};
GN ORFNames=MCYG_04763 {ECO:0000313|EMBL:EEQ31944.1};
OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ31944.1, ECO:0000313|Proteomes:UP000002035};
RN [1] {ECO:0000313|Proteomes:UP000002035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS995704; EEQ31944.1; -; Genomic_DNA.
DR RefSeq; XP_002847026.1; XM_002846980.1.
DR STRING; 554155.C5FPZ1; -.
DR GeneID; 9230142; -.
DR VEuPathDB; FungiDB:MCYG_04763; -.
DR eggNOG; KOG0401; Eukaryota.
DR HOGENOM; CLU_003998_0_0_1; -.
DR OMA; PRGGPNM; -.
DR OrthoDB; 92033at2759; -.
DR Proteomes; UP000002035; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 1.20.970.30; eIF4G, eIF4E-binding domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR022745; eIF4G1_eIF4E-bd.
DR InterPro; IPR036211; eIF4G_eIF4E-bd_sf.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF9; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED; 1.
DR Pfam; PF12152; eIF_4G1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101489; Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:EEQ31944.1};
KW Protein biosynthesis {ECO:0000313|EMBL:EEQ31944.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002035}.
FT DOMAIN 1133..1372
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 773..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 967..1131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1391..1536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..280
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..465
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..607
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..705
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..756
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..841
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1023
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1053..1074
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1391..1405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1453..1472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1536 AA; 164968 MW; 090C204F0309FFB3 CRC64;
MTSVSAHQDQ GTSDSPASTP ATVTKKSASQ TSTGETATPT ASSTSSHTQH GISPTLPPVN
AKAHMQNSSN PVSDGLTIVN GNTAPSVHSN SNNNPNINNS DHSRRQSVTI SAAGTSGFIP
NGGPASSGRP NNLRFGAVES SPRMGPPAVL ANQSQSSLGV GPSNSQGTSP HTSPSPIPQP
LASGGRPPSS LQGSGNNLNF RADMDNDPNR NMRGPQNHFR KESAHSNHGD MGQGMQGGGG
GGNRGGFHGG RGGRSGYSQG HHNHNHNQHQ HQHQHQHQHQ HQHQPQMPYN SPNQSYRSHP
PGRGGPNMDP RYNNAQQRPY GNYPNPPHQQ PIPSPALSHT NPATPQMASV PLTNPQMQAP
QYGAYPQPMA TQQVKQQLFP KFHGKRRSGS SYKKHSSHSS SNYNPAPYHH NVPIPLPQPP
PPLPQFTHPS YQPISYEPLP PPPPAQSAPQ SAPITQPPPG ELLQFPPPQE QQTPHISLSP
ESGNFEQLLT KFKSQGYPPP YDNNATYYYP NQYGMQPMPI VPSSPRNTYG MPHQQYMPAQ
YGAQPHQMPQ GVPIARSSSQ MSATDRPGSS VGQVPQPAGP GGPGHQHTGS RTNTASPVNQ
SQFVVPKKNS PLIIRDPGSG VVIKPSSSPA RGSASPAKLG VTPTSTPPPR TASRGEPDVS
DAKSQSGEEK KQSFQNAVVQ SLREKEAGEQ KSVAAKTEEK TAEKPAKPAA SAPETKAETT
DKPDKMVEEV VAEKTAPKEE EKKAPVEPAK PAADDEIDYD AIERELAELE AAEAAAEKAY
QEKKAKEQAE AALKAKESAA AEEEALKKAE REAEAAEEER IRKLESGENE ADRKERESLF
ASLRGKSATP AESPAIATPT ESGAATPVSD TSMGPPQKPL PGKREKPASL KLETNKQVEP
PQPSAAMKSL HSARFLEDPS NVSYPPSVVS PNPALNSNAP ADRKFKYNKE FLLQFQNVFK
EKPSVDWDAR VRETVGDGST DSARTPVRTP GPRSGASRGP SQGPMMGHFN QPVRTQTLPT
GSDRFPVMNA PRGSSKGGNP FGQFGPLNPM GARSASSAGS QLGGSRNPSH RGARTGSRQQ
KKKEEELSKT MPLTANLEIK PLNASGTGWK PRSIGSKTQT AAPDGHLPPD VVQGKVKSNL
NKMTPENFDK ISGQILDIVA QSKDESDGRT LRQVIQLTFE KATDEAHWAS MYAKFCMRMH
ESMSPEIKDE NIRDRNGTIV AGGSLFRKYL LNRCQEEFER GWKVNMPEKP EGVTEEVAMM
SDEYYKAAAA KRRGLGLVKF IGELFKLGML TERIMHDCVK RLVDYDGVPD EAEVESLASL
LRTIGASLDS SEKGHAMMDA YFARIKLMMD TTELQSRHRF MLMDVIDLRK AKWISKDADK
GPKTIAEIRE AAARAQQEQE MERARQQASR GGGGRMHLGR GDARNFSGYG AQVPPPDFSN
KVGSDDLRRL KTGRNTNQPA SFSPSGLLGS RSGSGRRNLG PGGNLVRGGE DSGASSRTGT
PPAGKDKKDE SSQNAFSALA GLDAGDSLAT SPPSNP
//
