ID C5FZL3_ARTOC Unreviewed; 413 AA.
AC C5FZL3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Pre-mRNA-splicing factor CWC25 {ECO:0000313|EMBL:EEQ35316.1};
GN ORFNames=MCYG_08135 {ECO:0000313|EMBL:EEQ35316.1};
OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ35316.1, ECO:0000313|Proteomes:UP000002035};
RN [1] {ECO:0000313|Proteomes:UP000002035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CWC25 family.
CC {ECO:0000256|ARBA:ARBA00006695}.
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DR EMBL; DS995708; EEQ35316.1; -; Genomic_DNA.
DR RefSeq; XP_002843052.1; XM_002843006.1.
DR AlphaFoldDB; C5FZL3; -.
DR STRING; 554155.C5FZL3; -.
DR GeneID; 9227797; -.
DR VEuPathDB; FungiDB:MCYG_08135; -.
DR eggNOG; KOG3869; Eukaryota.
DR HOGENOM; CLU_025093_0_0_1; -.
DR OMA; SWHPHTM; -.
DR OrthoDB; 12277at2759; -.
DR Proteomes; UP000002035; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019339; CIR_N_dom.
DR InterPro; IPR022209; CWC25.
DR PANTHER; PTHR16196; CELL CYCLE CONTROL PROTEIN CWF25; 1.
DR PANTHER; PTHR16196:SF0; PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG; 1.
DR Pfam; PF10197; Cir_N; 1.
DR Pfam; PF12542; CWC25; 1.
DR SMART; SM01083; Cir_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002035};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 10..46
FT /note="CBF1-interacting co-repressor CIR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01083"
FT REGION 102..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..265
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..324
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 413 AA; 48920 MW; E09B8DE6A4145820 CRC64;
MGGDLNVKKS WHPVLLKNQE RVWVEQKRAL EERKRIDQMM KERQEERQIQ ELQEMQEAAG
GKKRLNRVDW MYSGPAAGQA GTTEEMEGYL LGRRRIDGLL KGSENSKLEK TAPEDSFMLS
QNANTARDTA AKIREDPMLA IKKQEQAAYE AMMNDPARRR ALLKAAGMDE DRSTAHTEKE
RRHRRHRHRD DRDRDRDRDR DRDRDDERRS SHRSRRHHDE EDERRRSRHH RNRDRPRSVS
RSRSPPPRRS HRSPSPRRRR RSFSPRQRDR GRDRSRSPYR RREEESTRRH SSYRSHRSAG
PRRPKPEIHQ NHPLPPPPPP PQSADLERQR AARLAAMQQN ADELDEERTR RINAAEERDR
AEREAEEAAR AESSKYGGRG AFVNNIHRKA GDIDLADRLQ RGKKNLEKEQ EAY
//
