ID   C5FZQ3_ARTOC            Unreviewed;       787 AA.
AC   C5FZQ3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 66.
DE   SubName: Full=NWD1 {ECO:0000313|EMBL:EEQ35356.1};
GN   ORFNames=MCYG_08175 {ECO:0000313|EMBL:EEQ35356.1};
OS   Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX   NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ35356.1, ECO:0000313|Proteomes:UP000002035};
RN   [1] {ECO:0000313|Proteomes:UP000002035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS995708; EEQ35356.1; -; Genomic_DNA.
DR   RefSeq; XP_002843092.1; XM_002843046.1.
DR   AlphaFoldDB; C5FZQ3; -.
DR   STRING; 554155.C5FZQ3; -.
DR   GeneID; 9227650; -.
DR   VEuPathDB; FungiDB:MCYG_08175; -.
DR   eggNOG; KOG0266; Eukaryota.
DR   HOGENOM; CLU_000288_6_16_1; -.
DR   OMA; NAGHISH; -.
DR   OrthoDB; 2551282at2759; -.
DR   Proteomes; UP000002035; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR10039; AMELOGENIN; 1.
DR   PANTHER; PTHR10039:SF14; NACHT AND TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06670); 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002035};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          103..322
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REPEAT          626..667
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          748..787
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        751..778
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   787 AA;  89050 MW;  F75D7C476C27D908 CRC64;
     MSGLEKDTEI MAGHSYKNIQ ITGDARAQIG DIIHYHDRVL NRGLEQGNPL DTDCQCLNDL
     WPDNPDYEKE GIQKSKGGLL KDSCIWVLKN PEFLRWRGDQ QSRLLWVRGD PGKGKTMLLC
     SIIDELKKSN SEKHNLSFFF CQATNSQYNN ATAVLRSLIR QMVNQQPSLI KHVRKEYDNY
     RDIFKRINAW ITVCDIFKNI LEDRTLNHNF LIIDALDECT TGLTDLLNLV RQTSATYSNL
     KWIVSSRHWP SIEDSLNMAA QKSLLSLELN EESISAAVAI YIKHMVEKLA KEKNYSKGTE
     DKVHRRLSLN ANNTFLWVAL VCRELARREV RLHHIDSKLD AFPPGLDQIY QRMMDQISNS
     EDAILCIRIL AIVSVVYRPI TLDELMTFID LPDGFSNNEY LAEIIRLCGS FLTVKGPTIL
     FIHQSAKDFL VGNPSKEKIF PSGIKNEHYT IFSQSLQAMS RILRRDIYNL KVQQPKQDPL
     AVVRYSCIHW VSHLIDYYSD QAPGPEEDSL GRIIYGFFSE TYLYWLEALS LFGSSSEGIL
     AISKLEYILQ GSAERSQLIY LIQDARRFIL NHKHVIENWP LQIYSSALIF SPARSLVKDL
     FASEEPVWVR MKPTVEDNWS ACLQTIKGHN SSVHSVAFSH NSMLIASASC DMTVRIWSTS
     SGDCLQSVEN GSRGPIISFD TTSSYLLTDI GAIPVPSVSD ITAAPRRSPF QGWGISSTPP
     FLNTSLLIDF VTATISEAHF QDEVAGYKSH ETDQETLSAT WGLSARDKGR SSGSGSRDGL
     SLHREGQ
//