ID   C5G096_ARTOC            Unreviewed;       601 AA.
AC   C5G096;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:EEQ35549.1};
GN   ORFNames=MCYG_08368 {ECO:0000313|EMBL:EEQ35549.1};
OS   Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Microsporum.
OX   NCBI_TaxID=554155 {ECO:0000313|EMBL:EEQ35549.1, ECO:0000313|Proteomes:UP000002035};
RN   [1] {ECO:0000313|Proteomes:UP000002035}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4605 / CBS 113480 {ECO:0000313|Proteomes:UP000002035};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS995708; EEQ35549.1; -; Genomic_DNA.
DR   RefSeq; XP_002843285.1; XM_002843239.1.
DR   AlphaFoldDB; C5G096; -.
DR   SMR; C5G096; -.
DR   STRING; 554155.C5G096; -.
DR   GeneID; 9227422; -.
DR   VEuPathDB; FungiDB:MCYG_08368; -.
DR   eggNOG; KOG0053; Eukaryota.
DR   HOGENOM; CLU_011302_1_0_1; -.
DR   OMA; HYQELDE; -.
DR   OrthoDB; 35837at2759; -.
DR   Proteomes; UP000002035; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR42699; -; 1.
DR   PANTHER; PTHR42699:SF1; CYSTATHIONINE GAMMA-SYNTHASE-RELATED; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002035}.
SQ   SEQUENCE   601 AA;  66452 MW;  329DDED6E193D4AA CRC64;
     MSVDQPVGGS VPPNTAHAIS VSLPTWEANV GYEEGDAKII NAMTTGYPRF FIHKSIQCLA
     NEVIARFGRQ GESAMLFPSS KSASCCKDFL LSKVAEEDKP EIRVIRLAMP PQITPAELNG
     ISSELYAVLY PQIYASVSKQ VWQHTGSGIS SRRGEFCLKA LRDGYLVEES QGHARVSKVD
     SVIHKGPKRY QKLGSCGSAK KVEPTMGEKS AMQASDGGEF GQFIEERFGR NLNMSLANNA
     KLAVRRRIAG SLTTDADSNV PPEVTPEQAR ISGLNEEHVF LFPTGMNSIF NVHQLLLSAR
     GPMKSICFGF PYIDTLKILE KWGPGVQFYG LCSTEELDDL ERRLESGERY LALFTEFPGN
     PLLRSPDLER IHSLSKKYEF AVVVDESLGN FINVNVLPFA DVVVSSLTKI FSGDSNVMGG
     SAVINPHGQF YGRLKQVLAK EYEDDYWAED AVFLERNSRD FVVRVERINK SAEILTSLLE
     VSPLTKEVYY PKSSPTKCFY DKCRNQDGGY GGLFSVTFHT PEAAAAFFDN LSVLKGPSLG
     TNFTLSCPYT ILAHYQELDW AKSLNVPSDL VRISVGLEDV DDMNKRITYA LEAVERLGKG
     T
//