ID C5KT69_PERM5 Unreviewed; 740 AA.
AC C5KT69;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Ribosome biogenesis protein BOP1 homolog {ECO:0000256|HAMAP-Rule:MF_03027};
GN ORFNames=Pmar_PMAR001217 {ECO:0000313|EMBL:EER12419.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER12419.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03027}.
CC -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC {ECO:0000256|HAMAP-Rule:MF_03027}.
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DR EMBL; GG676168; EER12419.1; -; Genomic_DNA.
DR RefSeq; XP_002780624.1; XM_002780578.1.
DR AlphaFoldDB; C5KT69; -.
DR EnsemblProtists; EER12419; EER12419; Pmar_PMAR001217.
DR GeneID; 9057618; -.
DR InParanoid; C5KT69; -.
DR OMA; WEAMAPE; -.
DR OrthoDB; 5472008at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR HAMAP; MF_03027; BOP1; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR17605:SF0; RIBOSOME BIOGENESIS PROTEIN BOP1; 1.
DR PANTHER; PTHR17605; RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03027};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03027};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03027}.
FT DOMAIN 94..359
FT /note="BOP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01035"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..75
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 83652 MW; 1DFA0B543A6CC954 CRC64;
MPSAKKTRQV LAEASKPVNE EDAALQEIED SKALPGFEIG EDVVDNASTH GSTDDDEGEE
ESSETDDDDY DSDDSDDEYT RNRIGKVPLK WYLDNHDHIG YDISGKKIAR TVKTSEIDTL
LRAAEDPDAW RTITDIKNDR EIKLTDTDLR IIQRIRKGFF PTGRGDGDED EEFQVEYEDR
IEDKIHPLRT RYPSKKSFMP DQDEARTVKR LIKLIRAGII KPKEEKPGKE EEEEVFDAWA
DEEEGDEGRK LKGPAPIPAP KQALPTHGES YNPPEEYLFD DAEKAEWEAG DDSIRKQNYM
PQKFACLRHV PFYRDFLKER FERCLDLYLC PRVVKKKMNV DPLSLLPQLP SPSDLRPFPT
TVGVDFKGHS EKVTDSSFNV TGELLATCAA DGLRLWDTLS GCCLLHRGPN KAVVKQKNDN
AELVEAEVDV SPLCVAWHPK YSDILAVGTN NGTVELLRPQ CVKAAPAAEE EEEEAEDAPG
DEESESRRSN ASVELLAPVE DGDWEAVTDA PGFEGLLIRA DERADITKLT WHPRGWYLSH
VAPNAVQVRS QCVIHNLRSQ KTIRPFSKSK GGKIQASTFH PRKPQFYICT QKNVRLCDLK
AQSLVRTYVS GAQHIMAISV FPGTGEHLTI VSQDRRLCWF DNELGNKPWK TWRYHKRVVR
DVEFHPLAAG RLPLMATCSD DGSAHIFHAK VYNDAMSNPL VVPVKKLRPK DGGRILSCSW
HPHQPWVLLT MGDGRVQLWV
//
