ID C5KT82_PERM5 Unreviewed; 519 AA.
AC C5KT82;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
GN ORFNames=Pmar_PMAR001230 {ECO:0000313|EMBL:EER12432.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER12432.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Phe-tRNA synthetase alpha subunit type 2 subfamily.
CC {ECO:0000256|ARBA:ARBA00006703}.
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DR EMBL; GG676168; EER12432.1; -; Genomic_DNA.
DR RefSeq; XP_002780637.1; XM_002780591.1.
DR AlphaFoldDB; C5KT82; -.
DR EnsemblProtists; EER12432; EER12432; Pmar_PMAR001230.
DR GeneID; 9057631; -.
DR InParanoid; C5KT82; -.
DR OMA; QIEGWVM; -.
DR OrthoDB; 4619at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR Gene3D; 1.10.10.2320; -; 1.
DR Gene3D; 1.10.10.2330; -; 1.
DR Gene3D; 3.30.1370.240; -; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004529; Phe-tRNA-synth_IIc_asu.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR InterPro; IPR040724; PheRS_DBD1.
DR InterPro; IPR040725; PheRS_DBD3.
DR NCBIfam; TIGR00468; pheS; 1.
DR PANTHER; PTHR11538:SF40; PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF18552; PheRS_DBD1; 1.
DR Pfam; PF18553; PheRS_DBD3; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:EER12432.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000313|EMBL:EER12432.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT DOMAIN 234..500
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 519 AA; 58584 MW; C0AFF73F2B2645EF CRC64;
MAPGLPLTRE TLLTVIDQGD GIKDSIILAQ SAGWDHAKLV GVIKSLESIQ YVTTTPFEEE
KWTTTEEGEQ YAALGSPEAQ VVAYVKGHSP CAQKDIMVSL GNVAKIGFGA AMKNGWLAMD
KATKAVSVSD KAEDSIEDTV AELLVKVGKG EASSLTKGDM DMLKKRKLIH LSKTTGFKVD
KTSNFRTEIV KQETELTQEM IQNKSWKDVQ FKPYNLKTAL GRDLGGGHLH PLLKVKTEIR
NILLLMGFEE MPTNRYLESS FWNFDALFQP QQHPARDAHD TFFITSPEST NRIPKGYMND
VKKMHEVGGY GSIGWRYDWS EEESRKNILR THTTAVSTRV LYEMGQDYIR TGVFKPKKCF
SIDRVFRNET LDATHLAEFH QVEGFVADRN LTLGNLIGVI REFFRRMGLT DLRFKPAYNP
YTEPSMEIFA FHPMLDKWVE IGNSGIFRPE MVRPMGIPED VSVIAWGLSV ERPTMIQYGI
GNIRELFGHK MDVTSLKKNP VCWLYPGEEA PAVAEEREL
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