ID C5L3N2_PERM5 Unreviewed; 1095 AA.
AC C5L3N2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Karyopherin beta, putative {ECO:0000313|EMBL:EER08611.1};
GN ORFNames=Pmar_PMAR017666 {ECO:0000313|EMBL:EER08611.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER08611.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG678922; EER08611.1; -; Genomic_DNA.
DR RefSeq; XP_002776795.1; XM_002776749.1.
DR AlphaFoldDB; C5L3N2; -.
DR EnsemblProtists; EER08611; EER08611; Pmar_PMAR017666.
DR GeneID; 9042450; -.
DR InParanoid; C5L3N2; -.
DR OMA; PKRFVQE; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 27..102
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1095 AA; 120759 MW; 6C321C80740194B6 CRC64;
MDQGQLNQFC ELLKGLMSPS NEVRKPAEQQ YQNTKAQNPD QVTQALLAVI TSPERDATLR
QQASILLRQN MRVLREKDFV WPKLSEPTKQ AVKSSLLSMV ASEANKTMRH KICDCIGELG
GYLCADNSNN QWPELLPTLL QMIASNEAAP KESGLRILVD LIPAVGSMLM QNSANDVVAV
LKGSMEHSDI QVKVQAVKVI CSIVESLPTR HWKPVQALCP MVLSTIQSLC TGTMDDEVND
CLESLIGVAD EEPAYFRPYL AELCRTGFGI AQAKDAIEDG PRQLAFEMIT SLAEKKAKMC
MKVPNFITDA VKTCLIFMLE IDGDGDDTEA WCKRFADQDD DEDVTNYEVG EENIDRFAQA
LGAEKTLPVV FQAVAEFIRI GTWKHKVAAI MTLSQVAEVV EEETQMDEIV KLLLQHMGDQ
HPRVRYAALH AMGQTATDCT PYVQEAWSQE VLTALEKAMD DPIPRVASHA CAAFVNYAED
VEQEALIPHV KVLMEKLYRK LQMDQPRQIR EQAITAIAVI AGVSESHFVN YYSHIMPLLK
QTVQQASSKD ERTLRGKAFE CLSLLGLAVG KEVFANDAVE AMQAIVSMLR EPEKHFEDDD
PLKGFVLESL QRISKTLGSD FGQFLPALLP LILSQLSLTA AEVDDASEQQ DMTMIMLAEG
KCVGLKTSAI EDLASALQTI SCFIENCGPA VYNPYVKDTA LKLRPLLDFQ FNDEVKSLAV
NVWSELISCA RRANDTATVQ DLLNSFVESM LKAMAQEDEL ELLEAEARGV ANCVKNAGPG
TLSEQAVSHI VEVCFTLLKE SFNRRADATA EEESGECDED EVDEIRNIKE MDECVRIAIT
EIGGALMREH KQLFVSTGGL QKSIELVQKL IDTRCMAQDR CLALYIVCDF LECLGPDSVQ
AWSIFMEPMV AAITDNNSSI RQAAAYGANV ACNIPQFGDI AATAAAQLYR AMQRPDARSK
DNIAAHENAV AALGNVCEKF EQRLGNDAGN YWAAWIKNLP IKQDEDEGKK THAQLVRLVK
EQRPGVLGAN NSNLGVIVHV LALVYKKDYS NALIDRAICE VLAGLGEATI GGLQGSLNDK
SKKGVMRILN DAKSM
//
