ID   C5L570_PERM5            Unreviewed;      1225 AA.
AC   C5L570;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=Pmar_PMAR014893 {ECO:0000313|EMBL:EER08129.1};
OS   Perkinsus marinus (strain ATCC 50983 / TXsc).
OC   Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC   Perkinsus.
OX   NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN   [1] {ECO:0000313|EMBL:EER08129.1, ECO:0000313|Proteomes:UP000007800}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA   El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG679213; EER08129.1; -; Genomic_DNA.
DR   RefSeq; XP_002776313.1; XM_002776267.1.
DR   AlphaFoldDB; C5L570; -.
DR   EnsemblProtists; EER08129; EER08129; Pmar_PMAR014893.
DR   GeneID; 9064292; -.
DR   InParanoid; C5L570; -.
DR   OrthoDB; 5402874at2759; -.
DR   Proteomes; UP000007800; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd09076; L1-EN; 1.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR19446:SF415; REVERSE TRANSCRIPTASE-RELATED PROTEIN; 1.
DR   PANTHER; PTHR19446; REVERSE TRANSCRIPTASES; 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT   DOMAIN          820..1105
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   1225 AA;  139743 MW;  54312B29BE4F66D4 CRC64;
     MSVSPTDIAS LRQQIADLAN IMSSKQDVQV MKGSDGNVLG IQDCLVLIER KIKALEDKTN
     MSLSALNAKI EHTNERVGTI DARMSDYVSK LNDKIDNQSQ MMKDMYSLIS NMNKRGENQV
     GRYEETTSVL PKPRERVPAP VPSTQWSYTQ FDYKNNAKVV IFGVPEVDTT TEKEDGTPIL
     KPTVKEQVER ALTRAGARCA TDSMRTAKRL GAYRSDRDLE SRPRPICIQF AQPDVASEFV
     KANGVNLRKQ GLGIKWWRPY RPRASQATEE ISSMAARIDE LARLVKNHTL SAEKGVDGTI
     SGEGSDLLYP EQDYNMAGIV RQEREDRIGC TTQIVSLGSR GVGGNDGVCA FSEHELRSRE
     SRSNDIGHCQ LLTKSHKFLI ATLNIRTARK DRQMAKLVGL IERMELDITV VCESQVETES
     RMGSYRILNS SSKGVKIILS ERAENSMIKW TAHQDRIVSC RFFGKYFRTT VIGLYWPANN
     RNKRTEDYER FSHELDFVIS QVPPRDMLLI CGDFNCTGIN RDLLDTLAHT NDLCIGQWHK
     FKHLSTTPTW RHPNAELQGN VLDLILIRRR YVNMLEAMGV KDPRPVETDH RLVWARIGLH
     ICRGSGQRSR AMTERYIRRI CDSSPRRKRI DRELERATDE NDRIRSPDEE WDDFRSKLEH
     ATSQFEKSRT RTGCRDVVSQ HLKRKERRSR ITIAIEDMTK CHVNDDKALW KVIQDTFKVR
     SARATIPMSL TVDKVADYMS NMLYADGPVD NGRYGETDEL AITVPSEDHE PVPPDIKLNE
     VTEAIKRLKN KKSSGVDGLP AEVFKIGVGM AKSIQRVCQA CFETERLPEQ WDISKVTLIY
     KKGNKNECSN YRTILAQCAA AKIFSIIILA RIYPDIDRKI DNSQVAFRRG RSGLEVIHAL
     QLLIDKCNAF ELPLTLTSTD FRKAFDKISR DHVYESLRLA RVHPKYIRIV KNCYESAKAT
     IRLHKREQTI ELKSGLRQGD CWSPLLFICG LDRVLGQRIR ESQYGFRLVK EIQPGRYTRL
     SMRKQDLGLC LNELSFADDV TVPASTIEGA DRQLSYLEED GKIANLMIAP EKCKRLCVNL
     ESKEGSSEKS RIKCTDKLSI LGAIIDGKRD NETHIRRRMQ LAGQRMARLQ KVWNSHDISG
     RKREGWMDLI AEDLRVASLS RGDAQDRVLW ERRTKALRPR LRLKGTKATP RRGQGTGQFQ
     IFLGRDRPHK GQLAEEIYVT FSVSL
//