ID C5L617_PERM5 Unreviewed; 282 AA.
AC C5L617;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase, putative {ECO:0000313|EMBL:EER07826.1};
DE Flags: Fragment;
GN ORFNames=Pmar_PMAR026206 {ECO:0000313|EMBL:EER07826.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER07826.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; GG679674; EER07826.1; -; Genomic_DNA.
DR RefSeq; XP_002776010.1; XM_002775964.1.
DR AlphaFoldDB; C5L617; -.
DR EnsemblProtists; EER07826; EER07826; Pmar_PMAR026206.
DR GeneID; 9043033; -.
DR InParanoid; C5L617; -.
DR OrthoDB; 179007at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0044281; P:small molecule metabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42938; FORMATE DEHYDROGENASE 1; 1.
DR PANTHER; PTHR42938:SF9; FORMATE DEHYDROGENASE 1; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT DOMAIN 18..111
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 112..244
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EER07826.1"
FT NON_TER 282
FT /evidence="ECO:0000313|EMBL:EER07826.1"
SQ SEQUENCE 282 AA; 30833 MW; D9FB91C4CFF78D43 CRC64;
LLSSPFNKIA VDGIEKICKD NGLTFGKIEG YKTQEELYSA AESAEACIVR SDKLDEEFFN
RAKNLKIVVR AGAGVDTIDL DAASKHHVVV ENTPGQNANA VAEMVFALLI AMKRNHFDAT
SGREIRGSTL GLYGCGNVSR AMIEVSKGFA MKCYSYDPFL SDEQIKECGA EPLHDLKELF
KCDIVSLHVP ATPQTINSIN EDLMSLMPEN GVLVDAARSE VIDEDSVISI FQKRPDLGYI
SDVGFTKIDE LREKIGAAQL KKQLIVTPKK MGAQTLESNV NA
//
