ID C5L6K9_PERM5 Unreviewed; 964 AA.
AC C5L6K9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Amp dependent ligase/synthetase, putative {ECO:0000313|EMBL:EER07670.1};
GN ORFNames=Pmar_PMAR024076 {ECO:0000313|EMBL:EER07670.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER07670.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG679769; EER07670.1; -; Genomic_DNA.
DR RefSeq; XP_002775854.1; XM_002775808.1.
DR AlphaFoldDB; C5L6K9; -.
DR EnsemblProtists; EER07670; EER07670; Pmar_PMAR024076.
DR GeneID; 9042385; -.
DR InParanoid; C5L6K9; -.
DR OrthoDB; 1778695at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EER07670.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 516..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 825..848
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 854..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 896..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 930..952
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..142
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 693..753
FT /note="Carrier"
FT /evidence="ECO:0000259|Pfam:PF00550"
SQ SEQUENCE 964 AA; 108416 MW; 1795B4C8128F669C CRC64;
MPMNIAEVVR DMAKDQHVGK RTAAFECNTG MDTVKTTTYE ELWEKAMNLA RGIRERLGIR
EGTYQGLIAA CYMDRTIDWY VVYIACAALG LPLAAMGTDL PSKAQQEARN TYIMEELKPV
IVIADRAVDG DWDYTLREVL HELVHYKNTV LNFIPTEKSV CVVHNGLVHW SSAAYGILSI
GLSMGAMVAL PGSDYNLQKD LATFIEIASS VHARLTKRRR TLVCGFVPTV LSTIRKECVV
ERARLGGDND MVLISWGEKL SQELADEWND AKEITLLDLL IASEYWLSFY ATRDRQCHYE
NARYRVTEGA IIDVDEVLTR GQDQALVGEL LLGGDMVTPY GYYVPKGGDS RAERNNAEKF
VVRSGIRFYR TNDLVRVHPD KTVEFIGRIG NYVKLGGAFH DINVIQGQLS EELERSCYVV
NYEGQLHLFI THRDGCDRIN GSRLLAAVRS RIPMMDVENV HMLPANYELP RSEATGKLSG
PMLVNAVTKA DNRKAIEKKA EDTMEDVEAE RMRGTALMIT LALPLWSLLS HPFIILKAFF
MRLMLLPWVM RLLIHPAGEY VAYYTPFGRY GGPAMLRQDV ETWIGYVTKW GLAGVSKWYV
EQLEKLCNRK YYWRCSRLLH RVNSLLAVSG GPAETTTTRW TPQEYGKCSR CRRRYALNYG
CSDTFYAEPW NWYCEDCWWT HIGRIKGNSV EQKVLRILTA ILGEPPTSET TLMGLSSLNV
VLLTAQVNKE FGANLSVAEV MDSGTSLQVL CKRIEMAVIA AQPDDTTPPP HLVPAGVANM
MPAVHKKGAE EFQDLVNVNL DLSSRCSHPQ EGIDMIFNAG KLLHLSLQLT IALLAVNIVD
TLVVVALYEE AELVRLLYAV LNTVVFGSLG FYGFYRGFRG MVEEITDDLD AFRFAQTLLT
IVMVCFAFVP CGSIEGLLSD AMLDRHTHGF WFVSATIESV GWLLDALLSW YVTAKIKDLM
QPDV
//
