ID C5M1V4_CANTT Unreviewed; 1801 AA.
AC C5M1V4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Nucleoprotein TPR/MLP1 domain-containing protein {ECO:0000259|Pfam:PF07926};
GN ORFNames=CTRG_00043 {ECO:0000313|EMBL:EER35304.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER35304.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER35304.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692395; EER35304.1; -; Genomic_DNA.
DR RefSeq; XP_002545262.1; XM_002545216.1.
DR STRING; 294747.C5M1V4; -.
DR EnsemblFungi; CTRG_00043-t43_1; CTRG_00043-t43_1-p1; CTRG_00043.
DR GeneID; 8302177; -.
DR KEGG; ctp:CTRG_00043; -.
DR VEuPathDB; FungiDB:CTRG_00043; -.
DR eggNOG; KOG4674; Eukaryota.
DR HOGENOM; CLU_002593_0_0_1; -.
DR OrthoDB; 2730913at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR InterPro; IPR012929; TPR/MLP1.
DR PANTHER; PTHR18898:SF2; NUCLEOPROTEIN TPR; 1.
DR PANTHER; PTHR18898; NUCLEOPROTEIN TPR-RELATED; 1.
DR Pfam; PF07926; TPR_MLP1_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 1175..1301
FT /note="Nucleoprotein TPR/MLP1"
FT /evidence="ECO:0000259|Pfam:PF07926"
FT REGION 1..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1692..1801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 236..386
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 412..453
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 504..538
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 601..663
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 720..930
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 980..1305
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1337..1667
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..72
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1692..1711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1735..1755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1763..1784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1785..1801
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1801 AA; 205612 MW; 87EC70B11E955767 CRC64;
MSEDISNKDI ITVEDQSEEK QLVVEESAQA LETSEQQIEE SATTEQTPIE IDDAEKDTEH
QEDEKEQQHQ SEQQQEDQQS EQVQDVGNDS IQEDPHTSFL QPPASEKQFT TPSKDLPALK
DIEPITTPKT FAVAKDAIED QENLHGDGDT NNNNNHNSHD DSTPIVASSP MKHNILADLE
MHNEDTIDED SLRAISGYLS LDESSIRSIN NSSVLQALVS KSVEFQNITS ENEFLKLKLE
QNAQSIGKQL DDLKQKYSQS DNLATTLKDE KEKLELNYKQ QQQEFANLKE GKDNIERELL
QLKTSESAKD EELNKLRDAQ GQFEMDFEQQ INQLSSTNIT QSKKLNELTK EINETRNDKF
TLQLDLTKAQ NEISYLRDQK EWFENELKSA QSRFTDLIKK HESEYISTTS NVSNFQIRNE
TLEKLKQQLE STVDDLKSKL EQEITKSSKT ESEFELEKSR FLKEITSKEE LIELTKLQSE
QRASRIEQLE SYIEEVKDSM GETIASLESR LSEETEKLMK VEEKLRRTEE VLDAELHKET
DLPKLSDSSA MIAANGISLS TLYSEYNHLK KQLVLERSQK QKMEIQLESF IAELDARKPA
IANYREQIQF YENSMKEMIG KVETIRSEKT EVEKDAKRLR TVINENEIEL VSLKKLLKDL
GRQLCFYLIH SKIRDNNENP LTASEKRAIE KILDQSGRSD EQESDSDKLI TERLLEFKNI
IELRQKNEEL LVAIRNLSRK LESREDENNN LESVAIEEAK EAILTLESEL DSLNIKLDAI
TKERDALRSI NGKTATSNTN NNYLVQINED LKKKVDDCES IISKLREQSS KTVVDLNEKL
RVITDQKNEL SLKVSVSDKS AELANSRLSI VQKSFEDSRQ ELDQVRKEIN FWKQQTSKLE
ASLITKSEQL HQLEETLSSN KIAVASLERE REFKNVIQDS LQNEVNTLKQ DKTKLNEFVL
NLQSMLKERE ESAKEISSKL NASIDNYQSL HKKLSEKEER IFILSNQSEL SLKAQNAKLE
QVNEISRQLL ETKNMLVEKE NLVEELKKKL SSKRDIVVAP VATGVPAGGS TASNNESNNN
NLEIQQLKED LRIAESQVDE LTNLAKASET TLINATTSFE QYKHDSESKY QSLIKEKESL
EEEVKRVNEL YQTTTNNLEL AKTEHLAELN NLKSQLNEFR YKSDQYDALD KDYKEKLESI
RKDLQEQVKL ANESHNKYSI ELNKNVTLSE QISGLKDKLE VKEVEIKNLA EEVKITKKSV
EEQKDKLAVE KSQIETDLSM SNNKISELKE QNDLLLNQLE LTKQSVNGGS TGSENVDDLR
QVINYLRREK DSSDAKLLVA THENQELKIR LTNVENQIAA TSSTFNNSTS VINLDAKVQE
QKELSSQLEQ MNILKESNNN LRQENSKLVE EIGKLHSEVD NLRKELDPLK ATNNKLTTEL
EFAEQKVKLI EEENQRIKTS ATSTDEEKVE EAKKLHDSVQ KMQEQMSRLK EKANQRVLEK
SAIITEKDAN IQELNKKIQE LNNKIEELGK STKVSDESKD QINKSKEQID ELNKKLTSVS
EDLKKVVQEK NDLIKKLSDL ESNLRNQFEK EKQELSKTLQ SSKGSDSTVN KDLQENYNSL
LDRFVQEKKQ FESELETTKA KTREEVEKKY ELKLKMLTRK VDKYEKAMKN TTPATVPAKP
PIATGTPTLA TPGQASSGLV TAATPAAKST SGSPILAGKP VARPVGHPGN ESTLTVHRPG
PTHPFNESTL TVHRPAVSKT EPKKFSPSPN VSNTGGNGQQ ESRKRTNENQ QHRPQVKKAK
D
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