ID C5M1W4_CANTT Unreviewed; 3415 AA.
AC C5M1W4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
DE Flags: Fragment;
GN ORFNames=CTRG_00053 {ECO:0000313|EMBL:EER35314.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER35314.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER35314.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692395; EER35314.1; -; Genomic_DNA.
DR RefSeq; XP_002545272.1; XM_002545226.1.
DR STRING; 294747.C5M1W4; -.
DR EnsemblFungi; CTRG_00053-t43_1; CTRG_00053-t43_1-p1; CTRG_00053.
DR GeneID; 8299939; -.
DR KEGG; ctp:CTRG_00053; -.
DR VEuPathDB; FungiDB:CTRG_00053; -.
DR eggNOG; KOG1808; Eukaryota.
DR HOGENOM; CLU_000050_0_2_1; -.
DR OrthoDB; 1221059at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 7.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR048617; MDN1_AAA_lid_4.
DR InterPro; IPR041190; Midasin_AAA_lid_5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 8.
DR Pfam; PF17865; AAA_lid_5; 1.
DR Pfam; PF17867; AAA_lid_7; 3.
DR Pfam; PF21108; MDN1_4th; 1.
DR SMART; SM00382; AAA; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 6.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 317..467
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 654..916
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1088..1233
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1374..1584
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1755..1924
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2065..2332
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT NON_TER 3415
FT /evidence="ECO:0000313|EMBL:EER35314.1"
SQ SEQUENCE 3415 AA; 387693 MW; D74EABFC6DAEEE10 CRC64;
MDNHITVSLD QVEDLYSTYR SHYPLKKSLP RELFKFNKNS TIDENINQLA LKAIDHTLPI
YYCYKPIFLE ILARWITHTD EFEQEYKKSH PKMGNNIPGS IILLALSKLL QISHEYLNLF
ELFLSKYEFW SKIDTACTSE LETILLAFYR LLKFDTHRFK PFVQPKNLYQ IIKKVESKFG
VSKFLSIQVI SLYLQSSEIS KNKMIKAHLN DTTLLAKFED DEIDYSFITL IEAKRISNFL
SLPKNEFSLD VSKNCITITP EMLSPIVTSV CGILVPHLLI SSSSSNSSGE QQLEETKFVP
TNSAVEVLRK LASNIQFNKP VMLYGKAGAG KTFLINQLAN YMSYTDSIVK IHLGEQTDAK
LLLGTYASGE KPGTFEWRTG VLTSAVQEGK WVLIEDIDKA PTEVLSVLLT LLEKRELSIP
SRGEVIKAKN GFQLFSTIRT SNDSKKDAIP DLIGIRLWEL IKVEVPNELD LKNILVTKFP
LLVNLIGSFI KCYNEILRIY SLSSFVSLNK GSHPRVISFR DLMKFCGRCN NMLSLEGISE
PDQLVESSVF DNIFAEAVDC FGSAITEPQA LTPLINAIGE ALEIPTSRIN LFLSKHVPLF
INDEEKLKIG RATLKKSNTD KTLYNKRQGS NNSSFARTNH SLRLMEQIGV AIEMVEPVLL
VGETGTGKTT VVQQVAKLMN KKLTVINVSQ QTETGDLLGG YKPVNTKTVA VPIQEMFENL
FIGTFSEKKN AKFSKILTKC FNKNQWKNVI KLWSEALKMA KDLLSEPESE GEDGGAPRKK
RKLKSFEKSV LLEKWIEFEN KVKDFEIQAT TLDNSFVFNF VEGSLVKAVR NGEWLLLDEL
NLATSDTLES IADLLADTVN QRSILLSERG DVESIKAHPE FRIFGCMNPS TDVGKRDLPL
SIRSRFTEIY VHSPDRDIQD LLAIIDKYIG RFAVGDEWVG NDIAELYLKA KELSETNKIV
DGANQKPHFS IRTLTRTLIY VCDIVSIYGL RRSLFEGFSM AFLTLLDAKS EEVLKPEIVK
YTIGRLKNSK SVMSQIPPAP TSNSDDYVQF KHYWMKHGPH EIVPQPHYII TPFVEKNMLN
LVRATAGRRF PVLIQGPTSA GKTSMINYLA NITGHKFVRI NNHEHTDLQE YLGTYVSDST
GKLVFKEGVL VEALRKGHWI VLDELNLAPT DVLEALNRLL DDNRELFIPE TQEVVHPHPD
FMLFATQNPP GLYGGRKVLS RAFRNRFLEL HFDDIPQDEL EIILKERCQI APSYGKKIVE
VYRQLSIQRQ STRLFEEKNS FATLRDLFRW AMRDAVGYEE LAANGYMLLA ERVRKEDEKE
VVKKTIEKVM KVKLDMDAYY RSLEIEGIFN SDSTIVWTKA MRRLAVLVFT SIKYKEPLLL
VGETGCGKTT VCQIIAKFLG KELVTVNAHQ NTETGDLLGA QRPVRNKFET QSRLFNHLIE
IFTALEIKVG DDLTLEHLLT NYKALTIPDE LKDLANKIEE EKKNLTLLFE WSDGPLVRAM
KSGDFFLLDE ISLADDSVLE RLNSVLEPER SLLLAEKGTE DAFITAEETF EFLATMNPGG
DYGKKELSPA LRNRFTEIWV PSMEDFNDVH QIVESRITHK ELTSSIVKFS EWYAKQFGGG
HTNNGVISLR DILAWVEFIN SCDKTVTSPL AALYHGASMV FIDALGTNNT AYLAENESRL
QTIKKECVNK LSSFVDHDLL EFSNSKFQVT VNSSKLTAGL FSIPVIEGSE HNKSFNLDAP
TTAANAMRVI RAMQVKKPIL LEGSPGVGKT SLITALASAT GNPLVRINLS EQTDLVDLFG
SDAPAEGGKA GEFVWRDAPF LRAMQRGEWV LLDEMNLASQ SVLEGLNACL DHRGEAYIPE
LDKSFKRHPK FTVFAAQNPQ YQGGGRKGLP KSFVNRFTVV YVDTLKSDDL NMISQHLFPT
VDPEKCSKLI QFMSKLEEEV VTKKLWGSQG SPWEFNLRDS LRWLSLYTSG NISQDIQLSD
FIQMIVCQRF RNPEDRAKAK DLFESIFGPC DARDNYFNIS ESFVQAGGSL VARNELISYV
NGNSNLLSLQ CNYEFMETAF RCVSHNIPLI LTGPTNSGKT DLIRYLATSL GAKLDEFSMN
SDVDSMDILG GYEQVDLSRE TNALLDDTFK LINRLVVTNL RYKESDPEIL SKALDLLALI
ENGNHKQESF EGFRNALVEF SAYHSIPEIK ELVDSSNRLL KKINEEKSVK FEWFDGLLVQ
AVEKGNWLVL DNANLCSPSV LDRLNSLLET NGSLIINECS LEDGQPRILK PHPNFRLFLT
MDPKYGELSR AMRNRGIELF MNSLDKRITS FDSDILGIKK IDTSLDLADK VEESLTIEDQ
RPVPTFTFNF DKDTLLRSFS LIEDAFTSGE LSLSALWSLI PLANFENLIK WKEFVYSSSE
FGVVSKEFSS EICSTFGSVK EISLPSWLDK MYSESSTLAN EITGKRIHYD QYQSFHPLAN
IYIVVSFLEK HPEIKTSEST MLFETLGSII KLNNTVAKIE QMAMDKKVHD LSFIEKSAAS
QLGRDIKSRP RLEIYSFVKS LVTFINNLFF NSTKTSLLSE VVYKPLHELC LLVAGTIETA
EGKNESKLRV YQELITKWSE KYLVSNQELL KQFDAATSTF YQQFELTSGF AMNEIWESCR
GQYPQSFESW EILQRLFNLI EGFDKLSKVQ FPESAEVVSN FGILIGELYK SIISGDYDRN
EMQSIFAKLE QGISDLSTAS ESFNTARVNM FIEDFTNIAN FVELSGRNKE DLIKLYNFSE
RSMMSLIKET SFKPYPGIFD SLWVDNKPRV APLFTSQLTT SILNKTLGFN NTSGKLLDQA
NFDLKLVSKS IVKHSSDILK DQKKVFAELL TSWLSIILET IGLDGANEPG SILFEVTMKF
GPESPLMTVF AEYLVPALTI AKGSSDLKSL GRAWVLFSCG LIQLYVPSSP YDPAIKEYVL
YKVFEDQQKF ASDLISSWKA SRRVHNGDTE IFLESTLTDL VQLEAPSNPK VYRDGKSIDG
LFEEWNSIME SNIATEPIEK LLTSALSLSE MSENQIHMFQ NNTSQFIMRL DKNYMLYSDL
NDILRGYIYG LKLGFEIITL DSKQGKFYYP EDWSLDVSNF SSLSSIEKTF PYAKEFSKSV
KIDSPVSEFI MTYFMRLGFS HRSETTKANE ILMQALQQLY YRWSLRRIKE EKENIQSGSL
YKYSDPDEDI EGDFKKLFPD FEEVLDVDTT GSKKNNQSFE SIYESIAIAY IKEYLFGEKD
SLTDLAHEGS ELVSQLGKYS DQLQKSTNNA SSLTTLVNEL ASTHTKFNQS TSEFNFYQDA
NPSEVKRAVS IMTVVYNLSK KLLDQWPEHA TLKNIVFASN EFLSYPIGLP LGRYLQKLEQ
IYTFIAEWQK YASSQVSLKD QFDILTNLIN SWRKLELSTW KSLLKFEELS MKRIW
//
