ID   C5M4U2_CANTT            Unreviewed;       808 AA.
AC   C5M4U2;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 51.
DE   RecName: Full=Phospholipid/glycerol acyltransferase domain-containing protein {ECO:0000259|SMART:SM00563};
GN   ORFNames=CTRG_01920 {ECO:0000313|EMBL:EER35058.1};
OS   Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294747 {ECO:0000313|EMBL:EER35058.1, ECO:0000313|Proteomes:UP000002037};
RN   [1] {ECO:0000313|EMBL:EER35058.1, ECO:0000313|Proteomes:UP000002037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA   Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA   Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA   Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA   Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA   Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA   Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC       {ECO:0000256|ARBA:ARBA00007937}.
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DR   EMBL; GG692396; EER35058.1; -; Genomic_DNA.
DR   RefSeq; XP_002547613.1; XM_002547567.1.
DR   AlphaFoldDB; C5M4U2; -.
DR   STRING; 294747.C5M4U2; -.
DR   EnsemblFungi; CTRG_01920-t43_1; CTRG_01920-t43_1-p1; CTRG_01920.
DR   GeneID; 8301822; -.
DR   KEGG; ctp:CTRG_01920; -.
DR   VEuPathDB; FungiDB:CTRG_01920; -.
DR   eggNOG; KOG3729; Eukaryota.
DR   HOGENOM; CLU_349513_0_0_1; -.
DR   OrthoDB; 5478811at2759; -.
DR   Proteomes; UP000002037; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:UniProt.
DR   CDD; cd07993; LPLAT_DHAPAT-like; 1.
DR   InterPro; IPR022284; GPAT/DHAPAT.
DR   InterPro; IPR045520; GPAT/DHAPAT_C.
DR   InterPro; IPR041728; GPAT/DHAPAT_LPLAT.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   PANTHER; PTHR12563:SF17; DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR12563; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   Pfam; PF19277; GPAT_C; 1.
DR   SMART; SM00563; PlsC; 1.
DR   SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          211..344
FT                   /note="Phospholipid/glycerol acyltransferase"
FT                   /evidence="ECO:0000259|SMART:SM00563"
SQ   SEQUENCE   808 AA;  94191 MW;  F2B065B9DB352148 CRC64;
     MLPDVQTQSV SSAEDISNSD FDVNILQDLF TEPNVPLKFP LPTDKETYID IEGNGKEASK
     SFNILYSALR LITGPSRFDK IYSIQEYRYF TNKHSDEFKK KFNDYMNNKL ERDDTKLDEI
     VYDLINQELN LKLITADQFK ERFQKVKDYM VKFYKQQNKK NLPTFPSHEF LRSAYVTVLF
     LMRKLFPKGI WVSNDDISRL YQQYLKDPMS IIFLPSHQSH LDYIIIHVIC IRFQMGTPVV
     IAGENLNVAV LGGLLQNLGA IFIPRSFNNE LYTERNLNNV IEFFLMNKVS FEVFIEGTRS
     RDGKLLLPKY GILKTLCSIY DKQRNVDQNS NFDLLFQPVA VTYERVYEND AFLKELKGDD
     KTQESLFGTL SVAASAFFLK NDVVFDDKGW NDNSQRTLTG KIFVKLGESF KISEYLDSQS
     ELEKEMPDGV NLKRLGFKIL HEVNRNSYIP EVSIVGTAIQ AFYDFSNKSI FDVSELIPVL
     RIVVQALLRE NENSVTNSKI LEDMSVCSDA QLETLVKDQI FSFFRLIKVN KKTNSIKIES
     PIELLYYKNL TIHLIIKRCL VMYILLLLDG CPNCNHRVVG KIFYILTGFL KNEFLFDYDE
     NDRNELSFIL NDLVELQVVS KKEEDYQDSV YKIADHEYVK LFANLAQPFL ESYIVLISNI
     LEMTTNLADS YSRTKQQKKH DKIVVDDDEL RYPTTKGLLK YIIDKSKKRQ QFKSLESINK
     QYLVSDLYYL NNLQLVKIFK NKAKTKAFVQ ILNLKDLSVL NEFLHQLLQQ GTKKKNMLTN
     EIYVNYVIDI TDKNFDRDHD ELRLANKL
//