ID C5M5K0_CANTT Unreviewed; 322 AA.
AC C5M5K0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Protein-lysine N-methyltransferase EFM3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CTRG_01130 {ECO:0000313|EMBL:EER34270.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER34270.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER34270.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. EEF2KMT family. {ECO:0000256|ARBA:ARBA00005511}.
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DR EMBL; GG692396; EER34270.1; -; Genomic_DNA.
DR RefSeq; XP_002546825.1; XM_002546779.1.
DR AlphaFoldDB; C5M5K0; -.
DR STRING; 294747.C5M5K0; -.
DR EnsemblFungi; CTRG_01130-t43_1; CTRG_01130-t43_1-p1; CTRG_01130.
DR GeneID; 8295854; -.
DR KEGG; ctp:CTRG_01130; -.
DR VEuPathDB; FungiDB:CTRG_01130; -.
DR eggNOG; KOG2497; Eukaryota.
DR HOGENOM; CLU_038942_1_1_1; -.
DR OrthoDB; 53021at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF164; PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 322 AA; 36761 MW; 235DB8F48C10BB9F CRC64;
MNKQLFAYID QRVPARYLPI DDISFTYESQ LELVDHVNPI LSLNSFYVKS VLREYISRIE
KSNQDIADEL YELYCDPQIL NSKELDPSHP DIIKYYISGF NQSFTGNGQD TIIIKETPRL
ISGANTTGLR TWEAALYLSN FLNDIDSPPY DFRDKTILEL GCGTGLVSLA IAKSYHNKVG
NIRQVIMTDG STNVFDNITE TMQLNGLAES DIIKCQQLIW GEDTTISTDI DYIVAADITF
DSRILEPLCM TINDLFKNNN LQAGIIAATV RNIDTINDWE SQLEKWFPGR WNIVSGNRNP
HSIQSNCWFN VNTQEIRVYE IK
//
