ID C5MAJ5_CANTT Unreviewed; 788 AA.
AC C5MAJ5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN ORFNames=CTRG_03087 {ECO:0000313|EMBL:EER32662.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER32662.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER32662.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692398; EER32662.1; -; Genomic_DNA.
DR RefSeq; XP_002548790.1; XM_002548744.1.
DR AlphaFoldDB; C5MAJ5; -.
DR STRING; 294747.C5MAJ5; -.
DR EnsemblFungi; CTRG_03087-t43_1; CTRG_03087-t43_1-p1; CTRG_03087.
DR GeneID; 8297704; -.
DR KEGG; ctp:CTRG_03087; -.
DR VEuPathDB; FungiDB:CTRG_03087; -.
DR eggNOG; KOG1802; Eukaryota.
DR HOGENOM; CLU_010015_0_0_1; -.
DR OrthoDB; 2050054at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 3..32
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 62..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 788 AA; 89541 MW; 1857208D3E1AC97D CRC64;
MAIKCSTCHQ PFDHYDQLVL HIRNAKHLPG KLENQINIDY QKEIVCLASS FDKLSVTAAS
KNPLNNQSAS TPLRNVETNK TNAVGIFPNH KNKSRSKRSR PNGNNRAGAK SADNDTDEFV
KSYIKKFLPN SKPKINFHSM TEYSRHFTTL SFLQDITDNP RNITDKKDFK IIWNEEQALK
NKEYQIILTS ESELVKKMQD PDMLHLVSNP FIYESTIFMF NEIGQLWAGY VYRDETIKDK
NTQINHINLT IKLYDWNDKP LPRGQDTCGL KIYPASVQVT RMLNAMHCFS NTMLENIILG
KNPIYMDIYN NSTVDKLENK MLNESQRRAV FTSLYNPVTF LQGPPGTGKT SAIYEIVVQL
LQSNEYPILV TAASNVSVDN IAEKLMKSHP ETLIRIPATQ KLAEYDRKHP LASICLHHMV
YDSLTPEQQR IADRLYHKDV ASIDKCEFDS FCNARKKKSM EILSAHKVIF ATTTVAGGGQ
IKSLPQVRVV LIDEATQSAE PATLIPLALP RLKKVVVVGD DKQLSCLSEI KSLSMSMFER
LLLNNTCANP LMLDTQYRMH PQISEFPRLQ FCKGKLTDGI SSSERQEIGI THPLYFWDTD
GDAPESPIQN KKKADKGFTY VNPFEVAYVQ SVLRTLIQDK KINPSRIGVI TSYAGQRDVI
SSNLLQDRII NPDAEKLKQE VDLVNQRVRS AKGATINFVA GIMIATVDAF QGREKDIIVM
SCVRSNVDGS IGFLKDERRL NVSLTRAKYS MILIGDVECL KRRGKVWRNY FEFLKTKGAI
HKETEFVY
//
