ID C5MBU5_CANTT Unreviewed; 1373 AA.
AC C5MBU5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Bud site selection protein RAX2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CTRG_03537 {ECO:0000313|EMBL:EER33112.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER33112.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER33112.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; GG692398; EER33112.1; -; Genomic_DNA.
DR RefSeq; XP_002549240.1; XM_002549194.1.
DR STRING; 294747.C5MBU5; -.
DR EnsemblFungi; CTRG_03537-t43_1; CTRG_03537-t43_1-p1; CTRG_03537.
DR GeneID; 8297391; -.
DR KEGG; ctp:CTRG_03537; -.
DR VEuPathDB; FungiDB:CTRG_03537; -.
DR eggNOG; ENOG502QQZD; Eukaryota.
DR HOGENOM; CLU_005863_0_0_1; -.
DR OrthoDB; 2787019at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR024982; Rax2-like_C.
DR InterPro; IPR048266; Rax2-like_second.
DR InterPro; IPR048265; Rax2-like_third.
DR PANTHER; PTHR31778; BUD SITE SELECTION PROTEIN RAX2; 1.
DR PANTHER; PTHR31778:SF2; BUD SITE SELECTION PROTEIN RAX2; 1.
DR Pfam; PF12768; Rax2; 1.
DR Pfam; PF20842; Rax2_2; 1.
DR Pfam; PF20843; Rax2_3; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1373
FT /note="Bud site selection protein RAX2"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002952795"
FT TRANSMEM 1309..1330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 275..465
FT /note="Rax2-like second"
FT /evidence="ECO:0000259|Pfam:PF20842"
FT DOMAIN 477..637
FT /note="Rax2-like third"
FT /evidence="ECO:0000259|Pfam:PF20843"
FT DOMAIN 1028..1295
FT /note="Rax2-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12768"
FT REGION 69..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1373 AA; 152313 MW; 2BBC5F389E4CFBAA CRC64;
MKLSLQSLLF LITSITVLCH AADLFQPVSL PEFNYGDFGS RIGLFGSFEA LSFYSYINSS
QIVNPPTGSS NLLTKRDDVT NNTSSSSSTA SEPTDSLYIQ DIEQNFSLKF ADVNGQINQL
IVLTNETVLI NGNFTKFNNK SVISPIIYET SSKKITPIFE DDINGSVNTV FHDNGLIYLG
GDFKFNNTYS AAVYNISAEK VESTLFQGFG ENSVVNTIAK ILNNKNDDDS EENDQLGSIV
FGGQFDTLGL SDLLVHNITT NKTKNSNTSN TTIVSAEQLI SLRHGTFTTV NGQDSDEDAS
AIICPANGNE WAAIPNSGAE WRVQLPSEMK GVQPTKARLY IPEGSNGIKL FRIYSYPNNG
IMNLTYIDPA TNELAYCDAW CPLLSFDDLN DHVENNIANA TELNEDSSVF VDEENGSYFQ
YYDPSTNTKN LGYGSDFQEF AFVNEVGVDE VIVTIVDWYG EQGILAGFEL YQNAITVYGN
NTLNEPNCDF DFSSDNNNYA EINSGTFESI QEIDSGVTDY DYLVTHDTTA KMTLFPNISY
SGNYSIIMTT PGCASDNSCS QRAIVNVTVF GDHDNILATN LIYQNNENFK FDYLFYGHLN
GSTTTSGTNR IEISYHDRVD PSSEEPFMVV DKVIANIVSL DSIYDKNSTN HTRNSTRSEL
TTIKLNGLFE YSLANFSYFD ESLVHYKRNN RTYISQNNTF VGNSSINLLS GRFSNDTVVD
QIILQGNDSL MLLGNFKSDS ENLTLSNNNL LQLSIESYNS TANETIINLP NRLLKRDSQS
ILGGSFNNSI SRLINLPQGV LAIGDFALDV SGSSDIKDLS NDNETVSSAN NFALYSDKQW
YSFGNDYEPT SFNQFTNVTI NGTEYYVFSG DGVFRTWDNG NLTWVTDSNR QLNLSQAAVL
NERQQILGGS GFNTMDFYTT DQAYISDGKF NQFGIEVNKN VSFIITNSFY VNSSLSIIGG
RFESNNVKNV GFIDNNNPEN AMRSLQGNAT WGDDTMIQSL YVDNNNEYLF MGVNGSVAIG
DSSNLTGIVI YDLINDTFTS FQPPVLSNSN GDPIEVNSMV LFNEGNRLLV GGDFDLAGSL
SCPSLCVYDI ENTRWINPQD SNDQSISVSG VVTDMKFFQS NQALIVGTNL TLNNSNVNFL
TYNFQTAAFA TKDTLNDIDA SVERFILNDE NNKNLNGRLV AMGQDSIYGF DGTHWNRIDD
DIVYENYTTF NDIKLLTLSS SSNYNGTYFD KSNILTVAGI FDLKDYGLVN MALYNGTSWI
PYVFTSQSSD SSNSLEIGDI RSILIDDSNR FQSSDDLKSK NRFLSRGKVV GISLACALGS
TTLLGLLYII PYFALFRPRK DGYVPAQRIE ENEMMNAVNP EDLLHEIDLQ REK
//
