ID C5MC45_CANTT Unreviewed; 688 AA.
AC C5MC45;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Association with the SNF1 complex (ASC) domain-containing protein {ECO:0000259|SMART:SM01010};
GN ORFNames=CTRG_03637 {ECO:0000313|EMBL:EER33212.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER33212.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER33212.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase beta subunit
CC family. {ECO:0000256|ARBA:ARBA00010926}.
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DR EMBL; GG692398; EER33212.1; -; Genomic_DNA.
DR RefSeq; XP_002549340.1; XM_002549294.1.
DR AlphaFoldDB; C5MC45; -.
DR STRING; 294747.C5MC45; -.
DR EnsemblFungi; CTRG_03637-t43_1; CTRG_03637-t43_1-p1; CTRG_03637.
DR GeneID; 8297771; -.
DR KEGG; ctp:CTRG_03637; -.
DR VEuPathDB; FungiDB:CTRG_03637; -.
DR eggNOG; KOG1616; Eukaryota.
DR HOGENOM; CLU_445500_0_0_1; -.
DR OrthoDB; 120305at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd02859; E_set_AMPKbeta_like_N; 1.
DR Gene3D; 6.20.250.60; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR032640; AMPK1_CBM.
DR InterPro; IPR006828; ASC_dom.
DR InterPro; IPR037256; ASC_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR10343; 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT; 1.
DR PANTHER; PTHR10343:SF84; ALICORN, ISOFORM A; 1.
DR Pfam; PF16561; AMPK1_CBM; 1.
DR Pfam; PF04739; AMPKBI; 1.
DR SMART; SM01010; AMPKBI; 1.
DR SUPFAM; SSF160219; AMPKBI-like; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 538..686
FT /note="Association with the SNF1 complex (ASC)"
FT /evidence="ECO:0000259|SMART:SM01010"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..184
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..297
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 77405 MW; B9163785FFE0DE61 CRC64;
MGNNTSTTGS TGSGIIRRGS ESTRKSTASA NYNNLNGKDH FNDNRVRKSS AGKNTNSLDE
EFSDLILHQV VTKPSNSNLV PQQSQSQSQS SQQPPPRQQQ QKKQLPHNQF SNDLIEDEFN
ELNEVLVETD STALQRNILP DDGFENENSS SSDTTPTTND STTVTDDMDI DEPFPQDYDA
GSDVEDEDEI MNNAPDRSTT PTPDLTKVDF TKITSQKPPS LSNENVSVPP PAQMLSAASV
ARSVHSPSPN LENQKYLQQR PSKSMKTDQS TTPQNHNYHH HHHHNQHNHH YHNHNNHNRQ
KQQILIPIEI KWVNVTKEQI NKIAIIGSFS NWRDVIKMYP STSHPNEFVT TINLPLGVHK
LLYIINNEYR VSDQLPTATD QEGIFFNWFE VIDDTHLFNH SMNQPNHIGA STDYDANIIK
FEEPAMAQSP QYQQQQQQQH VYGASGSPMN NITPRPAGKY DVDRIHQKSA ELMHKISKES
TSEFEHVEFI EDTQSDQLLP PQVTQPNDIY GTSYENTQYQ PFDLSSNNSN SFLAANAVNE
PTYEYSSEIP EMFINYDYFK LKPSNYELPE PPQLPPHLNN VLLNKISSSG SSSSSGSVHT
HIPTNISSNS GGLSSTSTIN SIKRPPLRRA DSSYYASSKE SYHLQIPNHV ILNHLMTTSI
KNDVLTVACI TRYSGKFVTQ IMHSPADK
//
