ID C5MER5_CANTT Unreviewed; 344 AA.
AC C5MER5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Transcription initiation factor IIB {ECO:0000256|ARBA:ARBA00013932};
DE AltName: Full=General transcription factor TFIIB {ECO:0000256|ARBA:ARBA00031706};
GN ORFNames=CTRG_04558 {ECO:0000313|EMBL:EER31775.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER31775.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER31775.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the TFIIB family.
CC {ECO:0000256|ARBA:ARBA00010857}.
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DR EMBL; GG692400; EER31775.1; -; Genomic_DNA.
DR RefSeq; XP_002550260.1; XM_002550214.1.
DR AlphaFoldDB; C5MER5; -.
DR STRING; 294747.C5MER5; -.
DR EnsemblFungi; CTRG_04558-t43_1; CTRG_04558-t43_1-p1; CTRG_04558.
DR GeneID; 8301089; -.
DR KEGG; ctp:CTRG_04558; -.
DR VEuPathDB; FungiDB:CTRG_04558; -.
DR eggNOG; KOG1597; Eukaryota.
DR HOGENOM; CLU_043736_1_0_1; -.
DR OrthoDB; 38673at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20551; CYCLIN_TFIIB_rpt1; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR023486; TFIIB_CS.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618:SF13; TRANSCRIPTION INITIATION FACTOR IIB; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS00782; TFIIB; 2.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:EER31775.1};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Protein biosynthesis {ECO:0000313|EMBL:EER31775.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT DOMAIN 19..52
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
FT REGION 64..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 37977 MW; C92D29084DBD2E02 CRC64;
MSPSTSTAVQ EYVGPNLNVT LTCPECKIFP PDLVERFSEG DIVCGSCGLV LSDRVVDTRS
EWRTFSNDDQ NGDDPSRVGD AGNPLLDTED LSTMISYVPD NTKVGRELNR AQSKSLVDKK
DNALAAAYVK ISQMCDGYQL PKIVSDGAKE VYKMVYDEKP LRGKSQESIM AASIFIGCRK
ANVARSFKEI WALTNVPRKE IGKVFKIMDK IIREKNAANP NAAYYTQDSI STTQTSAEDL
IRRFCSHLGV NAQVTNGAEY IARRCKEVGV LAGRSPTTIA ATVIYMASLV FGIDLPPSKI
SDKTGVSDGT IKTSYKYMYE EKEKLIDPYW VESGKVKLEN IPKN
//
