ID C5MHY7_CANTT Unreviewed; 1391 AA.
AC C5MHY7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EER30684.1};
GN ORFNames=CTRG_05680 {ECO:0000313|EMBL:EER30684.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30684.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30684.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG692403; EER30684.1; -; Genomic_DNA.
DR RefSeq; XP_002551382.1; XM_002551336.1.
DR SMR; C5MHY7; -.
DR STRING; 294747.C5MHY7; -.
DR EnsemblFungi; CTRG_05680-t43_1; CTRG_05680-t43_1-p1; CTRG_05680.
DR GeneID; 8300895; -.
DR KEGG; ctp:CTRG_05680; -.
DR VEuPathDB; FungiDB:CTRG_05680; -.
DR eggNOG; KOG0920; Eukaryota.
DR HOGENOM; CLU_001832_4_0_1; -.
DR OrthoDB; 53793at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0022613; P:ribonucleoprotein complex biogenesis; IEA:UniProt.
DR GO; GO:0006396; P:RNA processing; IEA:UniProt.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd00048; DSRM_SF; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF05773; RWD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50908; RWD; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 423..518
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 596..765
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 821..987
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1391 AA; 157378 MW; 81ECF989AFABA5E5 CRC64;
MAKKGKSSKS TPEPISGGGG GGGKGKSKKD STPEPPTKNK KKNKDTSSDQ STTTTPAKPQ
RGLAIGDNFG WTGKLPVTLL NEHCQKQKWG RCQYDMIKKG SSGFIGIVTL NWENPKTKEL
ISIKLKGNYE PKETTNEARH MVATFVLHRI NYIKNMKMLL PVIFRDYWTQ LEDDRVKLLK
DNKELHDRLF NVNPFMVYMQ QKELEEKKEK ERLIKQQNEM KVKKPTISLG NNTTINKDKP
VSKRSIVLES ETTRKFPRKV WENAPFVDIP SEVRTSIEHS IRNHIDWVNT DHDLLKNSNS
TIVLNNLLSL GFREPHIKES FNYCSKFSDC LEWLLFHIPE DDLPPMFSKS DKDSKMQLKI
SSNLEFEYAL KRMSQSGFDE DEILEVYKKN NNDEHKTCVD LTQQLGPKIE TVNEPDSQDI
WNQEIEGLEI TGIPIKYEKN TATVKLNHEF LEVKIFKSEN YPNEFPGIQV IVPKSGYSLA
NYIKLSMIRQ LLDYLQSYVG ECMIYTIIDW LNENANKIIN NPGPLVKEKV SKTKIVTSNS
DIKSKRKASD KVSFITAKDI ENVKQSYTSR TSSSEYKDMI TQRQKLPAFA KKEALVSAIN
SNQVTLITGE TGSGKSTQVV QFIMDDLYSK GDFKTKIICT QPRRLSAISL ADRISKERTD
SIGQETGYII RGENKTGKNT RITFVTTGVL LRMLQSSKTN GILENIGYIL IDEVHERSVD
ADFLLILLKK MMKGFPKLKI VLLSATISIE TFVNFFSKPL TPLHIEGRTF PIEDYYLDNI
LSSLNYKIQN SDGEYVTPSP DSHFFKSGNI NYELIAKLAD YIDKKLTQEG NLGSILIFLP
GVLEISQTIK QINKENPNFM ALPLHSGLTS AEQKLIFKTP PKGKRKVVVS TNVAETSITI
PDCVAVIDTG KSKNLFFDTK LNTTKLIEDW CSQAEVRQRR GRSGRVTAGV CYHLYTKDTF
ESMKPQPIPE IKRTRLENLY LIVKSMGISN VDEFLSSGLD APDKSSLNKA NQILHEIGAL
QDNKLTKLGN YISYLPTDPQ SAKLLIMGCI FGCLDICLTL SAISSTGSPF INSFEQRDKL
KQIQRNFSNG QGDFISMANA YDAYMNKDRS KRFLNDNFLS YTTIKDITST RSQYLSLLTE
LGFVPRKYQE SDNKNSTNWS LVRAIVAGSF YPQIARVQYP DPKYFKSSSG SVEIDPDARQ
IKFWTKNTEQ KDDSLPASRV FIHPSSVLFN DKNSDFTVLD DEVLAKISHE DGTIDVEKAR
QLIDFKTPQL PKSSSSSSSS ALSKDSFIAF RSSHLTTKLY IRDITPTNPL SVLLFGGDFS
YDLSGVNSGQ LSHGIVIDNW LPIRTWCKNG VLIKHLRKIL DSLIDAKLSN PGQSTDIDDD
VYEVIQKIIN L
//
