ID C5MJ53_CANTT Unreviewed; 474 AA.
AC C5MJ53;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=B30.2/SPRY domain-containing protein {ECO:0000259|PROSITE:PS50188};
GN ORFNames=CTRG_06096 {ECO:0000313|EMBL:EER30312.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30312.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30312.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the cclA family.
CC {ECO:0000256|ARBA:ARBA00038149}.
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DR EMBL; GG692405; EER30312.1; -; Genomic_DNA.
DR RefSeq; XP_002546618.1; XM_002546572.1.
DR AlphaFoldDB; C5MJ53; -.
DR STRING; 294747.C5MJ53; -.
DR EnsemblFungi; CTRG_06096-t43_1; CTRG_06096-t43_1-p1; CTRG_06096.
DR GeneID; 8298745; -.
DR KEGG; ctp:CTRG_06096; -.
DR VEuPathDB; FungiDB:CTRG_06096; -.
DR eggNOG; KOG2626; Eukaryota.
DR HOGENOM; CLU_014420_4_0_1; -.
DR OrthoDB; 5479497at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR CDD; cd12872; SPRY_Ash2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR037353; ASH2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR10598; SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR PANTHER; PTHR10598:SF0; SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 110..294
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 246..280
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 54950 MW; 06F6586A31A4D4D1 CRC64;
MNKDVSEEPS IEPQVQGNES IGDNQSEETH LTRFKERKRE EELQRKSKLK QKEHNVVIHP
RLKPVPFKNS DLAPSSTPDQ NEVITIEGIK FGQIEDLPFN KRGFKYKHCR PNPGFVSNLY
STTDDKPYEV RTSLFDRSAG ILLSEDLSTI TTSQGWRSAR TNVCIREGSY YFEFRILKAD
EKSHVRIGIS RKEASLEAPV GFDGYSYGLR DVDGQFMTIS RRQKLCVEGG FRTGDVIGFL
VELPPLEKHR KAIEEFTMEK SILQRDQKQK RRKKKKVEQN IQDNVKFNQH GNILRDQIPI
KYKNALYYEQ YEYTTTKTME HLLNPVTVFG EKAIIEMDDK TKNIPIIPES RIRVFKNGIE
QESITDMYSF LPTNLEDTED INLGPNTRQQ SNPNYRNTDD GSLGYYPMLS AFQYGVVQLN
PGPDFDFAPP PITTTKERVK PLSDRYNDQV VEQLYWDIID EVEAQYLDSF DLIR
//
