ID C5MJI0_CANTT Unreviewed; 453 AA.
AC C5MJI0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=Protein SOF1 {ECO:0000313|EMBL:EER30183.1};
GN ORFNames=CTRG_06223 {ECO:0000313|EMBL:EER30183.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30183.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30183.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat DCAF13/WDSOF1 family.
CC {ECO:0000256|ARBA:ARBA00005649}.
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DR EMBL; GG692406; EER30183.1; -; Genomic_DNA.
DR RefSeq; XP_002546745.1; XM_002546699.1.
DR AlphaFoldDB; C5MJI0; -.
DR STRING; 294747.C5MJI0; -.
DR EnsemblFungi; CTRG_06223-t43_1; CTRG_06223-t43_1-p1; CTRG_06223.
DR GeneID; 8301562; -.
DR KEGG; ctp:CTRG_06223; -.
DR VEuPathDB; FungiDB:CTRG_06223; -.
DR eggNOG; KOG0268; Eukaryota.
DR OrthoDB; 5472351at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR007287; Sof1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22851:SF0; DDB1- AND CUL4-ASSOCIATED FACTOR 13; 1.
DR PANTHER; PTHR22851; U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN; 1.
DR Pfam; PF04158; Sof1; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002037};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 82..124
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 125..164
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 318..349
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 361..402
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 394..451
FT /note="Sof1-like protein"
FT /evidence="ECO:0000259|Pfam:PF04158"
SQ SEQUENCE 453 AA; 51460 MW; 7F1026BA39A49C55 CRC64;
MRLSLLQQQP TNQLTNHLAM KIKTISRSSD TYVPVKNTQE SALPRNLNPA LHPFERAREY
TRALQATKLE RIFAQPFVGQ LGDGHRDGVY GLSKNYNTTN QVASSSGDGI IKYWNLTDRL
ETASFKAHYG MISGICIHNN QMFSCGDDKT VKVWSVNTDD FDHKINDDEV YTNKGSRTTG
GSSKTSGGLI KTFIGEHSFK GIDHHREDDL FVTGGAAIQL WDINRSKYIS NLSWGCDNIN
TVKFNQSETN IIASTGSDNS IVLYDIRTNT PVHKAVTSLR NNALCFNPME PFNFASACDD
TNAYSWDMRK MEKPKKTYKG HVAPVMSVDY SPTGQELVTG SWDKTIRIFP ALNGRSRDVY
HTKRMQRVSA VMFTTDSKYI LSGSEDTSIR VWRARSDQRS AVKSARERAK LEYDDKLKER
YQYMPEIRRI ANHRHLPKVV KKAEEIRRNS SKK
//
