ID C5WQV3_SORBI Unreviewed; 460 AA.
AC C5WQV3;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Patatin {ECO:0000256|RuleBase:RU361262};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361262};
GN ORFNames=SORBI_3001G433900 {ECO:0000313|EMBL:EER95163.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EER95163.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EER95163.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- FUNCTION: Lipolytic acyl hydrolase (LAH).
CC {ECO:0000256|RuleBase:RU361262}.
CC -!- FUNCTION: Possesses non-specific lipolytic acyl hydrolase (LAH)
CC activity. Hydrolyzes phospholipids as well as galactolipids. May play a
CC role in disease resistance. {ECO:0000256|ARBA:ARBA00025642}.
CC -!- DOMAIN: The nitrogen atoms of the two glycine residues in the GGXR
CC motif define the oxyanion hole, and stabilize the oxyanion that forms
CC during the nucleophilic attack by the catalytic serine during substrate
CC cleavage. {ECO:0000256|RuleBase:RU361262}.
CC -!- SIMILARITY: Belongs to the patatin family.
CC {ECO:0000256|RuleBase:RU361262}.
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DR EMBL; CM000760; EER95163.1; -; Genomic_DNA.
DR RefSeq; XP_002468165.1; XM_002468120.1.
DR AlphaFoldDB; C5WQV3; -.
DR STRING; 4558.C5WQV3; -.
DR EnsemblPlants; EER95163; EER95163; SORBI_3001G433900.
DR GeneID; 8054325; -.
DR Gramene; EER95163; EER95163; SORBI_3001G433900.
DR KEGG; sbi:8054325; -.
DR eggNOG; KOG0513; Eukaryota.
DR HOGENOM; CLU_000288_144_1_1; -.
DR InParanoid; C5WQV3; -.
DR OMA; CIADFFD; -.
DR OrthoDB; 518048at2759; -.
DR Proteomes; UP000000768; Chromosome 1.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd07199; Pat17_PNPLA8_PNPLA9_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR32241; PATATIN-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR32241:SF3; PATATIN-LIKE PROTEIN 6; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU361262};
KW Lipid degradation {ECO:0000256|RuleBase:RU361262};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098,
KW ECO:0000256|RuleBase:RU361262};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 80..285
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 460 AA; 48988 MW; CF4249698F70AC0C CRC64;
MDDAEEMQVE RLQEEADAGG ADTDKLSYEI FSILESKFLF GYTDPHQLWL PKPPTPQASA
AAPGKPSAAA QRGKVCVLCV DGGGGGLRAL LAGRALAHLE AALRRASGDP DARVADYFDL
AAGTGAGGVF AAMLFSTHSR GAPLFHADDT WRLVADHAPR MFRRPGSSSS TSLFCRGKKR
PLAAPTAALE AAMKSAFGEE LTLRDTIKPV LISCYDLKTS APLVFSRADA LENESYDFRL
CEVGRAAWSE AGRFEPAEVA SVDGATSCAA VDGGPTMGSP AAAAITHVLH NKHEFPFVRG
VEDLLVLSIG GCSGGGSGAA GEAELRRMRR WGPKEWARPI ARIAADGAAD LVDHAVARAF
GQCRSSNYLR IQAKRESMPP CGPDGEYDPS PGNVRALLAA ADEMLKQRNV ESVLFEGRRV
GEQTNAEKLD WFAAELVAEH RCRGSRIAPT VAFKQAPQKP
//
