ID C5XFD3_SORBI Unreviewed; 940 AA.
AC C5XFD3;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=Formin-like protein {ECO:0000256|RuleBase:RU361260};
GN ORFNames=SORBI_3003G389100 {ECO:0000313|EMBL:EES04039.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES04039.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES04039.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|EMBL:EES04039.1}
RP NUCLEOTIDE SEQUENCE.
RA Paterson A., Mullet J., Bowers J., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A., Chapman J., Feltus F.,
RA Gowik U., Grigoriev I., Lyons E., Maher C., Martis M., Narechania A.,
RA Otillar R., Penning B., Salamov A., Wang Y., Zhang L., Carpita N.,
RA Freeling M., Gingle A., Hash C., Keller B., Klein P., Kresovich S.,
RA Mccann M., Ming R., Peterson D., Rahman M., Ware D., Westhoff P., Mayer K.,
RA Messing J., Sims D., Jenkins J., Shu S., Rokhsar D.;
RT "WGS assembly of Sorghum bicolor.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
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DR EMBL; CM000762; EES04039.1; -; Genomic_DNA.
DR EMBL; CM000762; OQU88036.1; -; Genomic_DNA.
DR RefSeq; XP_002458919.1; XM_002458874.1.
DR AlphaFoldDB; C5XFD3; -.
DR STRING; 4558.C5XFD3; -.
DR EnsemblPlants; EES04039; EES04039; SORBI_3003G389100.
DR EnsemblPlants; OQU88036; OQU88036; SORBI_3003G389100.
DR GeneID; 8078678; -.
DR Gramene; EES04039; EES04039; SORBI_3003G389100.
DR Gramene; OQU88036; OQU88036; SORBI_3003G389100.
DR KEGG; sbi:8078678; -.
DR eggNOG; KOG1922; Eukaryota.
DR HOGENOM; CLU_007699_0_0_1; -.
DR InParanoid; C5XFD3; -.
DR OMA; KMSTSHR; -.
DR OrthoDB; 623207at2759; -.
DR Proteomes; UP000000768; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF368; FORMIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..940
FT /note="Formin-like protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010960867"
FT TRANSMEM 107..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 479..909
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 42..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..74
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..373
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..429
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 940 AA; 100859 MW; 95CBA6F4EC93CD06 CRC64;
MPSPRQFLQL LLPILLATCC VDGGNGPDDA LATARRQLHQ PFFVPDQPGQ PSAPPPFFPA
MPVTPPPPMP TGQNQPTYPA LVLPNTGSSG ATPPAGSSHG SKKASKLVPA ILLPLLTVAV
LGLSVAFFFS HRRSNAARGG GGGCVGGGDA KFLHPERTSL FARDEFGGSG GGGGGGAAPA
PATSAEFLYV GTLASRADER SSDTTSSGDE ESRSSGGSPE LRPLPPLARQ CAPAPSRSPG
GGSPSSGEEE FYSPRGSSTK TTSSSRRTLA TAVQAALEAR DRSRTPSPGS VLSTPSYPSS
PGATLSPAPA SPPAFSSPGE SGRRSVKSRS ESARVVVLPP VPPTPPPPPP FAPTLPPPPP
PRRKPPSPSP PCSPLNDKSA LRSSTDTIEI NPFVQPPSLP TSTHPPRPPP AAGPPPPPPP
PPPPPVGYWE SRVRKPDTSK ETRSPALSPP PQAANFRSVP APTDAFPSRL PESSDQGDKS
EDTTPRPKLK PLHWDKVRAS SDRVMVWDQL KSSSFQVNEE MIETLFICNP ANAPAKEATR
RPVLPTPKAE NKVLDPKKAQ NIAILLRALN VTKEEVCDAL CEGNTENFGA ELLETLLKMA
PTKEEEIKLR EFKEETSPIK LNPAEKFLKA VLDVPFAFKR VDAMLYIANF ESEVNYLKKS
FETLESACDE LRSSRLFLKL LEAVLKTGNR MNVGTNRGDA HAFKLDTLLK LVDVKGTDGH
TTLLHFVVQE IIRTEGSRLS ASTQTTPRTQ ANPLREELEC KKLGLQVVAG LANELSNVKK
AAAMDSDVLS SYVTKLAGGI DKITEVLRLN EELKSRDDAW QFHDRMQKFL KKADDEIIRV
QCQESVALSL VKEITEYFHG DSAKEEAHPF RIFMVVRDFL TVLDQVCKEV GRINDRTIAS
SVRHFPVPVN PMMPQLFPRL HALRAGFSDD ESSAASVSSP
//
