ID C5XM95_SORBI Unreviewed; 1934 AA.
AC C5XM95;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00012589};
DE EC=2.4.1.34 {ECO:0000256|ARBA:ARBA00012589};
DE AltName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00032165};
GN ORFNames=SORBI_3003G179600 {ECO:0000313|EMBL:EES03079.2};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES03079.2, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES03079.2, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->3)-
CC beta-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:21476, Rhea:RHEA-
CC COMP:11146, Rhea:RHEA-COMP:14303, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:37671, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.34;
CC Evidence={ECO:0000256|ARBA:ARBA00000192};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 48 family.
CC {ECO:0000256|ARBA:ARBA00009040}.
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DR EMBL; CM000762; EES03079.2; -; Genomic_DNA.
DR STRING; 4558.C5XM95; -.
DR EnsemblPlants; EES03079; EES03079; SORBI_3003G179600.
DR Gramene; EES03079; EES03079; SORBI_3003G179600.
DR eggNOG; KOG0916; Eukaryota.
DR HOGENOM; CLU_3093705_0_0_1; -.
DR InParanoid; C5XM95; -.
DR OMA; WCPENGA; -.
DR OrthoDB; 211713at2759; -.
DR Proteomes; UP000000768; Chromosome 3.
DR GO; GO:0000148; C:1,3-beta-D-glucan synthase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0003843; F:1,3-beta-D-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046527; F:glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006075; P:(1->3)-beta-D-glucan biosynthetic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR026899; FKS1-like_dom1.
DR InterPro; IPR003440; Glyco_trans_48.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR PANTHER; PTHR12741:SF16; CALLOSE SYNTHASE 7; 1.
DR PANTHER; PTHR12741; LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1; 1.
DR Pfam; PF14288; FKS1_dom1; 1.
DR Pfam; PF02364; Glucan_synthase; 2.
DR Pfam; PF04652; Vta1; 1.
DR SMART; SM01205; FKS1_dom1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 515..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..652
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..716
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 763..782
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1495..1517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1553..1571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1642..1661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1667..1689
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1742..1761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1773..1793
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1814..1835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1841..1861
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1881..1898
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 342..457
FT /note="1,3-beta-glucan synthase component FKS1-like"
FT /evidence="ECO:0000259|SMART:SM01205"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1934 AA; 224136 MW; EED2966C8A4244E3 CRC64;
MASGGAGPSG PVRSTSQTRQ RTMGRIPTRA YTMRPDGLSG EDGPGFEEEE LVPSSLAPIV
PILRAANEIE EENPRVAYLC RFTAFEKAHL MDPISGGRGV RQFKTYLLHR LEKDEHETNR
RLATTDAKEI QRFYEQYCKK YLEEGHDKRK PEEMARHYQI ASVLYDVLKT VTPGKNEYDK
YAKGVEKEKA SFSQYNILPL NISTPRQPIM EIPEIKAAVA LLRQMDDLPM PRIELTQSSD
GKTVPDEMDK PLVQDLLDWL WQTFGFQKGN VENQKEHLIL LLANIDMRQQ GTSHHSGRHV
HVIHSSTVIY LMDKIFQNYN SWCRYLHLDS NIIIASDAST QRPELLYIGL YLLIWGEASN
VRFMPECLCY IFHHMARDLH DIISDRREGP FEPPFQREGS DDAFLQLVIQ PIYSVMQKEA
ARGKHGTVSH SMWRNYDDLN EYFWSKKCFK KLGWPMNPTA DFFADTRATN ETEQHDHVIS
RRRQHDHVIS RRRASKTNFV EVRTFLHLFR SFDRMWAFFI LAFQAMVIIA WSSSGALSSI
FEPEVFRNVL TIFITAAFLN FLQATLEIIL NWKAWKSLEC SQRIRYILKF AVAVAWLIIL
PTTYSSSIQN PTGLVKFVSN WINLQNESIY NYAVALYMLP NIFSALFFMF LPIRRVLERS
NSRIIRFLLW WTQPKLYVAR GMYEDTCSLL KYTTFWILLL ICKLAFSYYV EIAPLVEPTR
IIMSLERPPY EWHEFFPNLR HNLGVVVTVW APIVMVYFMD TQIWYAIFST ICGGVYGAFS
RLGEIRTLGM LRSRFEAIPR AFGKKLVPNH GSRLKRDEED KNPPFDKFAD IWNAFINSLR
EEDLLSNREK NLLVVPSSGG ETSVFQWPPF LLASKIPIAL DMAKSVKKKD EELMKRIKQD
PYTEYAVIEC YETLLDILYS IIVEQSDKKV VDRICESIKD SIHRRSLVKE FRLDELPQLS
VKFDKLLDLL KKYDENDPVN NNTQIANLLQ DIMEIITQDI MKNGQGILKD EGQKQLFANL
NLDSLKDVAW KEKCIRLQLL LTTKESAIYV PTNLEARRRI TFFANSLFMK MPRAPPVRSM
MSFSVLTPYF KEEVLFSPED LRKKNEDGIS ILFYLRKIYP DEFRNFLERI DFKPKDEEEL
KDRMDEICPW ASYRGQTLTR TVRGMMYYRK ALEIQCLQDT KDPAKFDQDG LIESYRELQS
SIEMAQAIAD IKFTYVVSCQ VYGMQKTSKD SKDKSRYQNI LNLMIINPSL RVAFIDEVEA
PTGNGATEKT YYSVLVKGGE KYDEEIYRIK LPGKPTDIGE GKPENQNHAI IFTRGEALQA
IDMNQDNYIE EAFKMRNVLE EFESRKYGKS EPTILGLREH IFTGSVSSLA WFMSNQETSF
VTIGQRVLAN PLKVRFHYGH PDIFDRLFHI TRGGISKASK TINLSEDIFS GFNSTMRGGN
VTHHEYMQVG KGRDVGMNQI SSFEAKVANG NGEQTLSRDI YRLGRRFDFY RMLSFYFTTV
GFYFSSMVTV LTVYVFLYGR LYLVMSGLER SIMLDARNQQ NVKALENALA SQSIFQLGLL
LVLPMVMEVG LEKGFRTALG EFVIMQLQLA SVFFTFQLGT KTHYYGRTIL HGGAKYRPTG
RGFVVYHAKF AENYRMYSRS HFVKGLELLI LLVVYLVYGR SYRSSSLYLF VTCSMWFLVA
SWLFAPFIFN PSCFEWQKTV DDWTDWRKWM GNRGGIGMSV EQSWEAWWLS EQDHLRKTSI
RALLLEIILS LRFLIYQYGI VYHLNIADHH KSIMVYGVSW VVMLLVLVVL KMVSIGRQKF
GTDLQLMFRI LKGLLFLGFV SVMAVLFVVL HLTISDVFAS ILGYLPTGWC LLLIGQACSP
LIRRTMLWDS IMELGRSYEN IMGLILFLPI GFLSWFPFVS EFQTRLLFNQ AFSRGLQISR
ILAGQKGIGE FEFE
//
