ID C5Y4F2_SORBI Unreviewed; 298 AA.
AC C5Y4F2;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Rx N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SORBI_3005G154300 {ECO:0000313|EMBL:EES09949.2};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES09949.2, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES09949.2, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM000764; EES09949.2; -; Genomic_DNA.
DR AlphaFoldDB; C5Y4F2; -.
DR STRING; 4558.C5Y4F2; -.
DR EnsemblPlants; EES09949; EES09949; SORBI_3005G154300.
DR Gramene; EES09949; EES09949; SORBI_3005G154300.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000288_137_2_1; -.
DR InParanoid; C5Y4F2; -.
DR OMA; WIAHEIK; -.
DR Proteomes; UP000000768; Chromosome 5.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProt.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR19338:SF53; RX_N DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19338; TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT DOMAIN 7..92
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 174..288
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 298 AA; 34348 MW; E8000F57C16D3CAC CRC64;
MEIATGAIST LLPKLGDLLK EEYKLQKSVR GEIMFLEAEL EAMQTVLLKI SSAPMDEQPD
AQVNLWVREV RELSYDLEDN IDRFLVRIDH APEQLHGLRG FIDRSLKLLT KVNLRRQIGT
DIRDIKTRIR EVSERHDRYK IDIVTAKATR PSVDSLRLSA LHKRASELIG TEEKVMDVVK
MLREEDDLSN QQLKIVSIVG LGGLGKTTLA NEVYKKLKAQ FECEAFVSVS LDPRMDQVFK
SMLRQLDKDK YNNIKGEMWD ETQLINELRY LLKNKSPKSQ VGDFIWSKQH YARMSTDG
//
