ID C5Z8W2_SORBI Unreviewed; 352 AA.
AC C5Z8W2;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 2.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EER88899.2};
GN ORFNames=SORBI_3010G249200 {ECO:0000313|EMBL:EER88899.2};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EER88899.2, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EER88899.2, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- FUNCTION: Transcriptional activator that specifically binds 5'-GATA-3'
CC or 5'-GAT-3' motifs within gene promoters.
CC {ECO:0000256|ARBA:ARBA00002206}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00357}.
CC -!- SIMILARITY: Belongs to the type IV zinc-finger family. Class C
CC subfamily. {ECO:0000256|ARBA:ARBA00007722}.
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DR EMBL; CM000769; EER88899.2; -; Genomic_DNA.
DR AlphaFoldDB; C5Z8W2; -.
DR SMR; C5Z8W2; -.
DR STRING; 4558.C5Z8W2; -.
DR EnsemblPlants; EER88899; EER88899; SORBI_3010G249200.
DR Gramene; EER88899; EER88899; SORBI_3010G249200.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_006493_0_2_1; -.
DR InParanoid; C5Z8W2; -.
DR OMA; CGISHRA; -.
DR OrthoDB; 3616433at2759; -.
DR Proteomes; UP000000768; Chromosome 10.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR045280; TIFY-like.
DR InterPro; IPR010399; Tify_dom.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46125; GATA TRANSCRIPTION FACTOR 28; 1.
DR PANTHER; PTHR46125:SF24; GATA TRANSCRIPTION FACTOR 28; 1.
DR Pfam; PF06203; CCT; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF06200; tify; 1.
DR SMART; SM00979; TIFY; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
DR PROSITE; PS51320; TIFY; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00094};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00357};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00094};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00094}.
FT DOMAIN 127..162
FT /note="Tify"
FT /evidence="ECO:0000259|PROSITE:PS51320"
FT DOMAIN 186..228
FT /note="CCT"
FT /evidence="ECO:0000259|PROSITE:PS51017"
FT DOMAIN 256..315
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..86
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 37509 MW; 9A78424B18CD4E8D CRC64;
MSHHDGSKPY QPRRGPERHP QPADGMAAPP PAAVGPSVEH LVAAAAEAEA LNRFAVEPQV
HEQEVGEEEE EDEEEDEMEE EEDEQEGQHG GIGGEHVPMD ADAAAAAAAA AGAQMDPHSA
MVPGTVPPMA TNQLTLSFQG EVYVFDSVSP DKVQAVLLLL GGRELSSLGG ASSSAPYSKR
LNFPHRVASL MRFREKRKER NFDKKIRYTV RKEVALRMQR NRGQFTSSKP KPDEIAASEM
AAVDGSPNWA LVEGRPPSAA ECHHCGTNAT ATPMMRRGPD GPRTLCNACG LMWANKGLLR
DLSKSPVPLQ VMQSAPLLDG GQNGNVMSAP GSELENAAAA MTNGHESSSS GV
//
