ID C5ZWW4_9HELI Unreviewed; 806 AA.
AC C5ZWW4;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=HCAN_0918 {ECO:0000313|EMBL:EES89632.1};
OS Helicobacter canadensis MIT 98-5491.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537970 {ECO:0000313|EMBL:EES89632.1, ECO:0000313|Proteomes:UP000007032};
RN [1] {ECO:0000313|EMBL:EES89632.1, ECO:0000313|Proteomes:UP000007032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 13241 {ECO:0000313|Proteomes:UP000007032};
RX PubMed=19542273; DOI=10.1128/JB.00729-09;
RA Loman N.J., Snyder L.A., Linton J.D., Langdon R., Lawson A.J.,
RA Weinstock G.M., Wren B.W., Pallen M.J.;
RT "Genome sequence of the emerging pathogen Helicobacter canadensis.";
RL J. Bacteriol. 191:5566-5567(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM000776; EES89632.1; -; Genomic_DNA.
DR RefSeq; WP_006655620.1; NZ_DS990368.1.
DR AlphaFoldDB; C5ZWW4; -.
DR STRING; 537970.HCAN_0918; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_008861_3_0_7; -.
DR OrthoDB; 5429313at2; -.
DR Proteomes; UP000007032; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007032};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 677..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..724
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 750..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 774..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 202..405
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 616..801
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 806 AA; 91246 MW; 1DF7DDF791251E25 CRC64;
MGLLFIFKTL LRYSKSILFV CFLVFLISLF YTLKLPIDAS SESLIAENNK DFKIYEEISQ
NYQSKDFLIL SFSPKNNDVF NPNSLKTLEN LINDIQKIPQ VESTLSILNA PLLKSTPTLE
LQEILKINPT LLSPQTDKNL AKKEILNHPF YTQNIISKNA KTTGILIFLK EDSKLKELLS
LKKSSTPLES QKIQNLIRTY KEQIQTQNTQ TIHSLKSLQA KYQTKGEIHL GGITLITNDM
IEYVKSDLIT YGTILSIILA LMLWIFFRQI YFVFLSFAVC LFTLIVSSGI FSFLGYQITI
VSSNYVSLLL IISVSLIVHL IVSYLEFYKK FPKASQKNLV FAVMLNKFSP SFFAVLTTII
GFLSLIFSSI LPIIHLGIIM SIGVSVALVS TFVLFGAILV LLPKPSKHRN IPKWHKNLLS
HCANIAINQP KLVYGIALLC TLFSIYGIFS LRVENSFVNY FKDKSEIKQG LLLIDKELGG
TIPLEIIIAF KKEESNNQST NFEDEFEAEF SALEKEDSYW FDSQKLRIAK NIHNYLSNKE
FIGSILSLHS LSILVESLGL GADDFMMAFL YKNSPQSLKD QLFTPYVNLE KNQMRFVFRT
FDSNPNLKRN AFIQEIQNDL TQILQKEPVS FQVNGIMVLY NNLLQNLIAS QVDTLSLVIG
AIFIVFILIF RSIKLSIIAL LTNLIPLGAI FGFLGISGIP LDLMGVTIAA ICLGIGVDDV
IHYIHRYKEE LKFHPIKTAI RNSHNSIGNA MYYTTLIIVI GFCAMMSSNF IPTIYFGLLT
TLVMLLMLIS SLILLPTLLM TFYAKK
//
