ID C5ZZ86_9HELI Unreviewed; 516 AA.
AC C5ZZ86;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=Flagellin {ECO:0000256|RuleBase:RU362073};
GN Name=flaB {ECO:0000313|EMBL:EES89344.1};
GN ORFNames=HCAN_0628 {ECO:0000313|EMBL:EES89344.1};
OS Helicobacter canadensis MIT 98-5491.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537970 {ECO:0000313|EMBL:EES89344.1, ECO:0000313|Proteomes:UP000007032};
RN [1] {ECO:0000313|EMBL:EES89344.1, ECO:0000313|Proteomes:UP000007032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 13241 {ECO:0000313|Proteomes:UP000007032};
RX PubMed=19542273; DOI=10.1128/JB.00729-09;
RA Loman N.J., Snyder L.A., Linton J.D., Langdon R., Lawson A.J.,
RA Weinstock G.M., Wren B.W., Pallen M.J.;
RT "Genome sequence of the emerging pathogen Helicobacter canadensis.";
RL J. Bacteriol. 191:5566-5567(2009).
CC -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC the filaments of bacterial flagella. Important for motility and
CC virulence. {ECO:0000256|ARBA:ARBA00025143}.
CC -!- SUBUNIT: Heteromer of FlaA and FlaB. FlaB is located proximal to the
CC hook while the remainder of the filament is composed of the predominant
CC FlaA. {ECO:0000256|ARBA:ARBA00025928}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362073}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362073}.
CC -!- SIMILARITY: Belongs to the bacterial flagellin family.
CC {ECO:0000256|ARBA:ARBA00005709, ECO:0000256|RuleBase:RU362073}.
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DR EMBL; CM000776; EES89344.1; -; Genomic_DNA.
DR RefSeq; WP_006655322.1; NZ_DS990368.1.
DR AlphaFoldDB; C5ZZ86; -.
DR STRING; 537970.HCAN_0628; -.
DR eggNOG; COG1344; Bacteria.
DR HOGENOM; CLU_011142_7_1_7; -.
DR OrthoDB; 9796789at2; -.
DR Proteomes; UP000007032; Chromosome.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.2120; -; 1.
DR Gene3D; 1.20.1330.10; f41 fragment of flagellin, N-terminal domain; 2.
DR Gene3D; 6.10.10.10; Flagellar export chaperone, C-terminal domain; 1.
DR InterPro; IPR001492; Flagellin.
DR InterPro; IPR046358; Flagellin_C.
DR InterPro; IPR042187; Flagellin_C_sub2.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR001029; Flagellin_N.
DR PANTHER; PTHR42792; FLAGELLIN; 1.
DR PANTHER; PTHR42792:SF2; FLAGELLIN; 1.
DR Pfam; PF00700; Flagellin_C; 1.
DR Pfam; PF07196; Flagellin_IN; 2.
DR Pfam; PF00669; Flagellin_N; 1.
DR PRINTS; PR00207; FLAGELLIN.
DR SUPFAM; SSF64518; Phase 1 flagellin; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362073};
KW Cell projection {ECO:0000313|EMBL:EES89344.1};
KW Cilium {ECO:0000313|EMBL:EES89344.1};
KW Flagellum {ECO:0000313|EMBL:EES89344.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007032};
KW Secreted {ECO:0000256|RuleBase:RU362073};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 5..143
FT /note="Flagellin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00669"
FT DOMAIN 430..515
FT /note="Flagellin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00700"
SQ SEQUENCE 516 AA; 53728 MW; 6EE137CE04AA2216 CRC64;
MSYRIYTNVN ALNAHTSGLV NNRNMSESLE KLSSGLRINK AADDASGMAI ADSLRSQAAA
LGQATRNAND AIGMIQTADK AMDEQIKILD TIKTKATQAA QDGQTTTTRN ALQSDILRLM
EELDNIANTT SFNGQQMLSG AFTNKEFQIG AYSNITVKAS IQPTNSHKIG HVRYETGAEM
SVSAGSSNLN EVTLRFLNTD GTNNYAIESI KISTSAGTGI GALAEAINKN SDTLGVRATY
NVMGQGAGAI ASGTVRGLVI NGIAIGDVND VQKNDYDGRL INAINAQKER TGVQASLSIS
GALQLTSTDG RAISVQVASG SSVLGGGSFA GVSGTTHAIV GRLTLIRLNA RDILVSGTNF
SQVGLHSGAT NIQNGSGIAQ YTVNLRSVNG EFDANIASAI GANANTAVAA VNSNGIGAGV
TSLEGAMAVM DMAQSAQEHL DKIRADLGSV QQQLVSTINN ITVTQVNVKS AESQIRDTDF
AEESANFSKT NILAQSGSFA MAQANQVQQN ILQLLQ
//
