ID C6A0X6_THESM Unreviewed; 349 AA.
AC C6A0X6;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=UPF0282 protein TSIB_0203 {ECO:0000256|HAMAP-Rule:MF_01406};
GN OrderedLocusNames=TSIB_0203 {ECO:0000313|EMBL:ACS89271.1};
OS Thermococcus sibiricus (strain DSM 12597 / MM 739).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=604354 {ECO:0000313|EMBL:ACS89271.1, ECO:0000313|Proteomes:UP000009079};
RN [1] {ECO:0000313|EMBL:ACS89271.1, ECO:0000313|Proteomes:UP000009079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12597 / MM 739 {ECO:0000313|Proteomes:UP000009079};
RX PubMed=19447963; DOI=10.1128/AEM.00718-09;
RA Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V.,
RA Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.;
RT "Metabolic versatility and indigenous origin of the archaeon Thermococcus
RT sibiricus, isolated from a siberian oil reservoir, as revealed by genome
RT analysis.";
RL Appl. Environ. Microbiol. 75:4580-4588(2009).
CC -!- SIMILARITY: Belongs to the UPF0282 family. {ECO:0000256|HAMAP-
CC Rule:MF_01406}.
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DR EMBL; CP001463; ACS89271.1; -; Genomic_DNA.
DR RefSeq; WP_012766232.1; NC_012883.1.
DR AlphaFoldDB; C6A0X6; -.
DR STRING; 604354.TSIB_0203; -.
DR GeneID; 8095175; -.
DR KEGG; tsi:TSIB_0203; -.
DR eggNOG; arCOG00969; Archaea.
DR HOGENOM; CLU_079268_0_0_2; -.
DR OrthoDB; 21331at2157; -.
DR Proteomes; UP000009079; Chromosome.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR HAMAP; MF_01406; UPF0282; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR014426; UPF0282_hydrls.
DR PANTHER; PTHR43546; UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED; 1.
DR PANTHER; PTHR43546:SF4; UPF0282 PROTEIN MJ1629; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR PIRSF; PIRSF004944; UCP004944_hydrls; 2.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009079}.
FT DOMAIN 17..80
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 349 AA; 40895 MW; E8F6380C72AECDEF CRC64;
MALSFRPIWF DSMGAKSSCV LVKTPDISVI IDPGIAIMQP SFPASEEKKI EWLIEGEKAI
KNASKEADVL VISHYHYDHY FPGDLEVYRG KRLLAKNPNE YINDSQRKRA DYFYSNLCRY
FGGLKLEDLW REREAKKYSN LMDKLPIAVS KDFGEYNTRR KQLLEKGLKW FENRADMWNR
SPKIPEVKFE DVEVHFADGR EFQFGDTKIR FTGPMFHGIE FSRVGWVIST VIEYEDEKLI
HSSDLNGPII EDYAEWIIKE NPNILILDGP MTYMLGYLLN KINLRRAVEN AVKIVRKIDA
EIIIYDHHLP RERHFKEHTK KVWETAERLD KNLLTAAEFL GMKPKVLEI
//
