ID   C6H4U4_AJECH            Unreviewed;       119 AA.
AC   C6H4U4;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=NADP-dependent malic enzyme MaeA {ECO:0000313|EMBL:EER45882.1};
GN   ORFNames=HCDG_01461 {ECO:0000313|EMBL:EER45882.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER45882.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG692419; EER45882.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6H4U4; -.
DR   STRING; 544712.C6H4U4; -.
DR   VEuPathDB; FungiDB:HCDG_01461; -.
DR   HOGENOM; CLU_2060823_0_0_1; -.
DR   OMA; PEMLMSE; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR012302; Malic_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF03949; Malic_M; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT   DOMAIN          1..45
FT                   /note="Malic enzyme NAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03949"
SQ   SEQUENCE   119 AA;  13152 MW;  83607015A2134393 CRC64;
     MIYASGEALS KTLTSEELEH GLLYPDLTRI RDVSVIVARG VIRAAQEAKV DRETGIRDLS
     DADMDAWIRS KMYAPHSEVA SLEREVGILL SSIGRPSYNN NNGWEMVSDE DANDKGAKL
//