ID C6H7U9_AJECH Unreviewed; 361 AA.
AC C6H7U9;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Mating-type switching protein swi10 {ECO:0000313|EMBL:EER43480.1};
GN ORFNames=HCDG_01510 {ECO:0000313|EMBL:EER43480.1};
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712 {ECO:0000313|EMBL:EER43480.1, ECO:0000313|Proteomes:UP000002624};
RN [1] {ECO:0000313|Proteomes:UP000002624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ERCC1/RAD10/SWI10 family.
CC {ECO:0000256|ARBA:ARBA00008283}.
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DR EMBL; GG692420; EER43480.1; -; Genomic_DNA.
DR AlphaFoldDB; C6H7U9; -.
DR STRING; 544712.C6H7U9; -.
DR VEuPathDB; FungiDB:HCDG_01510; -.
DR HOGENOM; CLU_041616_1_1_1; -.
DR OMA; GTTTCAM; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProt.
DR GO; GO:0006302; P:double-strand break repair; IEA:UniProt.
DR CDD; cd22325; ERCC1_C-like; 1.
DR Gene3D; 3.40.50.10130; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR047260; ERCC1-like_central_dom.
DR InterPro; IPR004579; ERCC1/RAD10/SWI10.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR010994; RuvA_2-like.
DR NCBIfam; TIGR00597; rad10; 1.
DR PANTHER; PTHR12749:SF0; DNA EXCISION REPAIR PROTEIN ERCC-1; 1.
DR PANTHER; PTHR12749; EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF03834; Rad10; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT DOMAIN 55..168
FT /note="ERCC1-like central"
FT /evidence="ECO:0000259|Pfam:PF03834"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 361 AA; 40538 MW; A93D57966F3D9362 CRC64;
MDDDFGDVPD FDVLLGPSKS DKSLPHTSAP EKLDQTRKVQ QPKPQALPSR SSPSSILVSA
RQRGNPILNH VRHVPWEFAD IPADYIVGST TCVLFLSLKY YRLHPEYIYS RIKGLAGKYN
LRILLTLIDI PNHEDSLREL SKTSLVNNLT LILCWSAAEA GHYLELFKSC EHAQPTAIRT
QQSQSYNESL VEFITTPRSI NKSDAASLIS TFGSLQAAVN AQAEQISTVP GWGEKKVQQW
HDAVRDDFQI QRTAKRSAKP STDNAKAAVM QQENFTFTEE ENAFLAAHSE KFSHDKPSQS
SETPSHRIPK NKLNSQDDME RENDSSKDDW PESNARPSGQ HEEQFNDGIV TALDKLREHG
D
//
