ID C6HRD6_AJECH Unreviewed; 1203 AA.
AC C6HRD6;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Bromodomain-containing protein {ECO:0000313|EMBL:EER37070.1};
GN ORFNames=HCDG_08521 {ECO:0000313|EMBL:EER37070.1};
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712 {ECO:0000313|EMBL:EER37070.1, ECO:0000313|Proteomes:UP000002624};
RN [1] {ECO:0000313|Proteomes:UP000002624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG692436; EER37070.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HRD6; -.
DR STRING; 544712.C6HRD6; -.
DR VEuPathDB; FungiDB:HCDG_08521; -.
DR eggNOG; KOG1472; Eukaryota.
DR HOGENOM; CLU_006198_0_0_1; -.
DR OMA; YRRSEAK; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR CDD; cd05510; Bromo_SPT7_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037782; Spt7.
DR PANTHER; PTHR47343; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR PANTHER; PTHR47343:SF1; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT DOMAIN 341..411
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1019..1203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1083..1119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1129..1144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1203 AA; 131346 MW; 406A3BB83BFBE606 CRC64;
MSIGQHHNWL LPGHLRPPDD HHDPHPSING LSKVPSRPRT PQLRFRGIAD GSQSGNMISD
ADTIPEEDPR IASFRDCYQK GEAKISALFN FGKASDPGNN EPGAIQGAEE TGIAADGQVQ
SSAPARKAAR KLDEDDYDDY DDDDESESAP PAPSPLIISK PAPARSEPNT LPSPPQKPSI
ALKTSETQKD PKKHSLEDIR KKLEEDKKAT EEAARRNFHT VFYTLENDRD AMLDQQMLEE
SERQVEAEMS GQGANSANSA NATTSGHGTL SSANLGASSL TLKNLIARID MKRSEVQASD
AELRSLMSEV RKNRSKWASE EKVGQEELYE AAEKVLSELK AMTEHSSAFL TRVNKREAPD
YYNIIKRPMD LGTMTKKLKA VQYKSKQEFV EDLNLIWTNC LKYNANPEHF LRKHALYMRK
ETEKLVPLIP DIVIRDRAEV EAEERRLQLA ELDGAEESDD EPIMSSRGRK APGMKSKKGI
GTGRTAPGSR PEATPGAENK TQGGTAVGAE SDTALEGSQN GFSTPPPGTL TPLGSNGLGP
GAAGSQGDAM DIDAFGVPVN SSALSRPMIE FEDPEYKIWK QVTKKDRALL AAERHRLFKG
DKLNADEPAL LRSKAGMRRW LRNQRPATEE ADRLDIAGPQ SKEVETTGET LAEGIEVEED
KMLPDYYDTM SGIPDLPEQL RWIEDSEGNV VDHSEEFLRI LPKGYFTSPK SKFSKKMDAN
MRQMQETRKV CSKIGIVKQM QLQSQMYQNQ FQKYNPEPFV EQDVPTHVMN DDGPVISPWV
CRAALQRSVG KIFYNAGFEE YQPSALDAVT DVAADFFYKI GSTLKTYMES PKIPRTEQST
VSSEWKSPYM AEEMILHTLQ SVGTDVESLE SYVKEDVDRL GQKLSIIHER MKSHLTELLR
PAFSDTTGDG SSAFNDGSEQ FVGGDFAEDI DEDFFGFKEL GLDKEFGLAS LSVPLHLLQN
RMYSAHQAQN TSSSQASAAL FPPPPPYPRI SLQTLPSQIG LVQNFFLAKL HANNDEPLVE
DLELPPKQRP TAARPRVPAS GKIPHAPLGT GLNSSPQKRP APPAGTGGSK PGAPEPSKKK
SKKNNGTAGP SNAELGNDES SNQTKSSTSA KTLGKQKVSS TVADDKAAVI SPKKSRHESS
ADGVVAESDS EIILSANNGN NDIKMNGSTS ATVNGADPPD LAVGGSSAIS GGGILSPESM
STR
//
