ID C6J268_9BACL Unreviewed; 334 AA.
AC C6J268;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Catabolite control protein A {ECO:0000256|ARBA:ARBA00019435, ECO:0000256|RuleBase:RU368079};
GN Name=ccpA {ECO:0000313|EMBL:EES72785.1};
GN ORFNames=POTG_02485 {ECO:0000313|EMBL:EES72785.1};
OS Paenibacillus sp. oral taxon 786 str. D14.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=621372 {ECO:0000313|EMBL:EES72785.1, ECO:0000313|Proteomes:UP000003981};
RN [1] {ECO:0000313|EMBL:EES72785.1, ECO:0000313|Proteomes:UP000003981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D14 {ECO:0000313|EMBL:EES72785.1,
RC ECO:0000313|Proteomes:UP000003981};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Allen-Vercoe E., Strauss J., Sibley C., White A.,
RA Lander E., Nusbaum C., Galagan J., Birren B.;
RT "The Genome Sequence of Paenibacillus sp. D14.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Global transcriptional regulator of carbon catabolite
CC repression (CCR) and carbon catabolite activation (CCA), which ensures
CC optimal energy usage under diverse conditions.
CC {ECO:0000256|RuleBase:RU368079}.
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DR EMBL; GG695978; EES72785.1; -; Genomic_DNA.
DR RefSeq; WP_009225204.1; NZ_GG695978.1.
DR AlphaFoldDB; C6J268; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_0_9; -.
DR OrthoDB; 9784962at2; -.
DR Proteomes; UP000003981; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06298; PBP1_CcpA; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR006377; CcpA.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR NCBIfam; TIGR01481; ccpA; 1.
DR PANTHER; PTHR30146:SF150; CATABOLITE CONTROL PROTEIN A; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|RuleBase:RU368079};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU368079};
KW Reference proteome {ECO:0000313|Proteomes:UP000003981};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|RuleBase:RU368079};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU368079};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU368079}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 334 AA; 37054 MW; 55296CF0AC478911 CRC64;
MTVTIYDVAR EAGVSMATVS RVVNNNPNVK PQTRKKVYEA IERLGYRPNA VARGLASKKT
TTVGVVIPDI SNSIFAEIAR GIEDIANMYH YNIILCNADK RKEKEIRVIN TLLEKQVDGL
LFMGGTVTEE HIQAFQTSAV PIVLCATSDE NGQYPSVDID HEAAAFDAVS TLIRHGHREI
AMISGTLQDP ANGYARFQGY KRALETAGIR YQEDLVRIGN YRYESGVEAM KYFLGLKKRP
TAIFAATDEM AIGAIHSIQD EGLKVPDDFS IISVDNIRMA SMVRPQLTTV AQPMYDLGAV
AMRLLTKLMK KETVENPRVI LPHETILRLS VSHL
//
