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Database: UniProt
Entry: C6J774_9BACL
LinkDB: C6J774_9BACL
Original site: C6J774_9BACL 
ID   C6J774_9BACL            Unreviewed;       290 AA.
AC   C6J774;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   08-MAY-2019, entry version 36.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:EES71092.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:EES71092.1};
GN   Name=hbd {ECO:0000313|EMBL:EES71092.1};
GN   ORFNames=POTG_04251 {ECO:0000313|EMBL:EES71092.1};
OS   Paenibacillus sp. oral taxon 786 str. D14.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC   Paenibacillus.
OX   NCBI_TaxID=621372 {ECO:0000313|EMBL:EES71092.1, ECO:0000313|Proteomes:UP000003981};
RN   [1] {ECO:0000313|EMBL:EES71092.1, ECO:0000313|Proteomes:UP000003981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D14 {ECO:0000313|EMBL:EES71092.1,
RC   ECO:0000313|Proteomes:UP000003981};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA   Berlin A., Borenstein D., Chen Z., Engels R., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Walk T., White J., Yandava C., Allen-Vercoe E.,
RA   Strauss J., Sibley C., White A., Lander E., Nusbaum C., Galagan J.,
RA   Birren B.;
RT   "The Genome Sequence of Paenibacillus sp. D14.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG696000; EES71092.1; -; Genomic_DNA.
DR   RefSeq; WP_009226967.1; NZ_GG696000.1.
DR   STRING; 621372.ACIH01000247_gene1406; -.
DR   PRIDE; C6J774; -.
DR   EnsemblBacteria; EES71092; EES71092; POTG_04251.
DR   eggNOG; ENOG4105DYT; Bacteria.
DR   eggNOG; COG1250; LUCA.
DR   BioCyc; GCF_000159955-HMP:POTG_RS21550-MONOMER; -.
DR   Proteomes; UP000003981; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000003981};
KW   Oxidoreductase {ECO:0000313|EMBL:EES71092.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003981}.
FT   DOMAIN        6    182       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      187    283       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   BINDING      49     49       Coenzyme A. {ECO:0000256|PIRSR:
FT                                PIRSR000105-3}.
FT   BINDING      56     56       Coenzyme A. {ECO:0000256|PIRSR:
FT                                PIRSR000105-3}.
FT   BINDING     119    119       Coenzyme A. {ECO:0000256|PIRSR:
FT                                PIRSR000105-3}.
FT   SITE        140    140       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   290 AA;  32469 MW;  CF7C08813667AD1D CRC64;
     MNYKRIGVIG GGTMGQGISE MLAAKGLDVL LVEETADKLD HAYNMIETSL EKQLEKWAIT
     KAEKKLILSR IHKVTHFAEL GTCDMVIETI SEDLNAKKEV FTQLDQVCPS NIILASNTST
     LSLTEIAGGT KYPERVIGMH FIYPVAKINL VEIIRGLKTS DTTFEETKRF VEEVVEKRGI
     MVYESPGFVT SRIICVMINE ALHVLGEGVA SAEEIDEAMR MGYQFQYGPL EMADRFGLDS
     VLAALERMFR EFGELKYRPS FVLKKMVRAG NLGVKTGEGF FKYDKDGDRL
//
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