ID C6KTA0_PLAF7 Unreviewed; 1159 AA.
AC C6KTA0;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=CRAL/TRIO domain-containing protein, putative {ECO:0000313|EMBL:CAG25077.1};
GN ORFNames=PF3D7_0626400 {ECO:0000313|EMBL:CAG25077.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CAG25077.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000313|EMBL:CAG25077.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C., Harris B., Harris D.,
RA Mungall K., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corto C., Cronin A., Davies R.,
RA Davies P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James D.,
RA Johnson D., Kerhornou A., Knight A., Kontfortov B., Keyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., McLean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M-A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
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DR EMBL; AL844505; CAG25077.1; -; Genomic_DNA.
DR RefSeq; XP_966247.1; XM_961154.1.
DR AlphaFoldDB; C6KTA0; -.
DR SMR; C6KTA0; -.
DR PaxDb; 5833-PFF1280w; -.
DR EnsemblProtists; CAG25077; CAG25077; PF3D7_0626400.
DR GeneID; 3885997; -.
DR KEGG; pfa:PF3D7_0626400; -.
DR VEuPathDB; PlasmoDB:PF3D7_0626400; -.
DR HOGENOM; CLU_275508_0_0_1; -.
DR InParanoid; C6KTA0; -.
DR OMA; PMSTFMK; -.
DR OrthoDB; 240766at2759; -.
DR PhylomeDB; C6KTA0; -.
DR Proteomes; UP000001450; Chromosome 6.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR PANTHER; PTHR46818:SF1; CRAL_TRIO_N DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46818; DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR SUPFAM; SSF69349; Phage fibre proteins; 2.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT DOMAIN 114..275
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT REGION 791..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 873..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1159 AA; 136290 MW; 7AB924D3CA5DDE64 CRC64;
MELSKGKVII EKDINEHTID DEVFMFEPSI DDVYDKNTNL RFIFHNTFIT SEEEIAISEF
RKYCKSRCLK INKIYFENEC LRYLYSAQFD FSKAMELIKS NYEFRLSSIL PIKEKDVIFY
INKGVMYWHG RDKKCRPILI INLLKVELLS IDDLSNLFFF CFEFFLKYLC IPGKIENYIS
IIDCSGISIS KFPMTTFMKL LEIMNSKYRC RLFRMYILEA PKILKTFGKS FLNFAPTYMT
KKLKILDNNY ADYLREEILS TQLEKKYGGI QEDKINNFYP FHFYPSCYIS QQQKRKSQDN
KAVIEKKTNI FNNDHIYNIF LSGYSMHVIL VQKDQRIIDN HRYNDILLND SNSANLERTA
CIEADTSDNH KEDADVIKKN VHKDMVKSMS IDSLKQISSD NLKYISSDNL KYISSDNLKY
ISSDNLKHIG SDNLKHIGSD NFKHIGSDNF KHIGSDNFKH IGSDNFKHIG SDNFKHIGSD
NFKHIGSDNF KHIGSDNLKH IGSDNFKHIS GDHHNNYYHK RKKKKKKKHI ILNEEELLLQ
QQFVNYMKNE EYDIENVHIL KNNKFINFKN KYVVHIDSIH KWIFKIKNLF LSNITINYIT
KRFPFLKNVI LVKSNFKCIN EYIKYLKENV PPEISTSHQI VSTNNEHDEE DNHKNKSNII
IKNNMNEKEE EIKKERLYNN PSTDKIINKF ENIQRLSSCK YVDDMKEEYN NNIKIGHHKH
DPNIMLKTEK GVKIKKNKKK IEIMENKNKN KSKNKISHDN TSKEYNYPEV NIYNNCESIF
DEYIKTSSMD NNKKKGFKEK NNDNNNNNNN NNTNIDNNDN NIDNNIDNNI ENNDNNNNNM
IMMMKKKNGE PENPCGDKVN LKKKGIENVK QKHKEVEISE EQGKLKQSSE TKGRLKQPHT
IKVTDRLFKE REDMEKNEKR EYIEKKILSK VTMNFSPCDK ETQSKKNKKK KKKGIDDVKF
ISMNKDELSN MLSKEYVEKG NINCDNMTCE SNTICDNSKS ENYIPLDNKT NNNNNNNNKK
SAISIKSIFP KRLDHALSKY KKYSTTSIST RLSRSSYNKF VSEDKNEENH FDNIVINDSY
QNKVSFFSQV SLSTGNITNT IDLDTNKNEK KNDVNFKSTI VDNSNKPVNP EVPEKKSRKK
LSKIKIIGLQ FFNKQSSRR
//
