ID   C6L8W0_9FIRM            Unreviewed;       487 AA.
AC   C6L8W0;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=MATE efflux family protein {ECO:0000313|EMBL:EET62699.1};
GN   ORFNames=BRYFOR_05049 {ECO:0000313|EMBL:EET62699.1};
OS   Marvinbryantia formatexigens DSM 14469.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Marvinbryantia.
OX   NCBI_TaxID=478749 {ECO:0000313|EMBL:EET62699.1, ECO:0000313|Proteomes:UP000005561};
RN   [1] {ECO:0000313|EMBL:EET62699.1, ECO:0000313|Proteomes:UP000005561}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14469 {ECO:0000313|EMBL:EET62699.1,
RC   ECO:0000313|Proteomes:UP000005561};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EET62699.1}.
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DR   EMBL; ACCL02000001; EET62699.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6L8W0; -.
DR   STRING; 168384.SAMN05660368_01680; -.
DR   eggNOG; COG0534; Bacteria.
DR   Proteomes; UP000005561; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd13134; MATE_like_8; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   InterPro; IPR047135; YsiQ.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR   PANTHER; PTHR42925:SF2; NA+ DRIVEN MULTIDRUG EFFLUX PUMP; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005561};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        41..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        423..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   487 AA;  53080 MW;  4BCB97DF96E823F2 CRC64;
     MLDIRCLLYY YYSSAKINRQ GRDGMKYREK AKRNGEFYKK LFALVMPIAM QNLMSAIVSA
     SDALMLGMQG QTALSAVSLA TQVSFVLNLF YAALTIGATV LAAQYWGKGD RRAVEQVLAI
     VLRLSVIVSV LFFLAAVCCP KLLMRIFTNG TELIAPGASY LRIVSGSYLC MGVSQIYLCI
     MKNSGRTMRS TIYGSSAVVI NLILNAVFIF GLCGFPVMGI RGAALATLIA RIAELLLVLS
     ENRKEEVVRI RLQYLRAPDS ALKKDYIRYT TPVLANELVW GCGFTMFSVI MGHLGSDAVA
     ANSIANIVKN IIACFCLGIG AGSGIIVGNE LGRGNLEKAK EYGRKLCRIA LAAGALSGIV
     LLALSPVIFL FASNLSLLAK EYLKGMLLIC SYYLIGKSIN STVVAGIFCA GGDTKFGLCC
     DAVTMWVIII PAGAIAAFVL KLPVLWVYFW LNLDEFVKLP AVYHHYKKYK WVKNLTVENA
     GMDSGQE
//