ID C6LIE1_9FIRM Unreviewed; 594 AA.
AC C6LIE1;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Adenylate/guanylate cyclase catalytic domain protein {ECO:0000313|EMBL:EET59637.1};
GN ORFNames=BRYFOR_08495 {ECO:0000313|EMBL:EET59637.1};
OS Marvinbryantia formatexigens DSM 14469.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Marvinbryantia.
OX NCBI_TaxID=478749 {ECO:0000313|EMBL:EET59637.1, ECO:0000313|Proteomes:UP000005561};
RN [1] {ECO:0000313|EMBL:EET59637.1, ECO:0000313|Proteomes:UP000005561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14469 {ECO:0000313|EMBL:EET59637.1,
RC ECO:0000313|Proteomes:UP000005561};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET59637.1}.
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DR EMBL; ACCL02000017; EET59637.1; -; Genomic_DNA.
DR AlphaFoldDB; C6LIE1; -.
DR STRING; 168384.SAMN05660368_01928; -.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG4252; Bacteria.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000005561; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005561};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 321..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 414..546
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 594 AA; 65329 MW; 157F89B3DF7393DF CRC64;
MIKNKRNLAA ALVIAAVTFA AAYFQWFASL NLSLQDAVYQ RENRADTSIK IIAIDEKTLE
ALGQFETWTR EPYAELIELL DGGEYAPGAI GLDILMVSEK GEEDQLLVDA CKKYDNIVMA
CNLVFSTQIE TENGKSTVNQ LHIDMVETPF GELADIVQMG FVNTVQDYRD NSVRYTLLEC
GGYESFASAI VRMAENGRQT ETTETENERQ TSANHGIFID YTGGPDTYET VSMIDVLEGR
IPAAAFADSI VLVGAHAAGM GDAYSVPSGK GAQMYGVEIH ANIIQSLLEG RSLVQVSRFW
NALCYASIAF ALTLLAVRMK IAVNVLGAAV IIAGWYLFCL KLDEKGVVIH MISFPLSVLV
VLVWSIVSKY AAEVLQRRKI MHAFRKYVAP QVVEEISKHH DYRLKLGGEK RHIAVLFVDI
RGFTPLSEAL EPEQVVEILN EYLGLVTDAI FKNGGTLDKF IGDAAMAVFN APFDSEDYVY
KAVCAARDIA AGSDRIAAKF MERFGKKVSY GIGVNCGDAV VGNIGSDFRM DYTAIGDTVN
TAARLEANAG AGQIFISEFV YERLKERIEV TEIGEIPLKG KSRGVMVYAL DRVR
//
