ID C6T7L5_SOYBN Unreviewed; 453 AA.
AC C6T7L5;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Chloroplast fatty acid desaturase 8 {ECO:0000313|EMBL:AEE25912.1};
GN Name=FAD8 {ECO:0000313|EMBL:AEE25912.1};
GN Synonyms=100799517 {ECO:0000313|EnsemblPlants:KRH65715};
GN ORFNames=GLYMA_03G056700 {ECO:0000313|EMBL:KRH65715.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:ACU17817.1};
RN [1] {ECO:0000313|EMBL:ACU17817.1}
RP NUCLEOTIDE SEQUENCE.
RA Cheung F., Xiao Y., Chan A., Moskal W., Town C.D.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRH65715.1, ECO:0000313|EnsemblPlants:KRH65715}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH65715};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH65715.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [3] {ECO:0000313|EMBL:AEE25912.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:AEE25912.1};
RA Upchurch R.G., Ramirez M.E.;
RT "Soybean Plastidal Omega-3 Fatty Acid Desaturase Genes GmFAD7 and GmFAD8:
RT Structure and Expression.";
RL Crop Sci. 51:1673-1682(2011).
RN [4] {ECO:0000313|EnsemblPlants:KRH65715}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH65715};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KRH65715.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH65715.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; BT093448; ACU17817.1; -; mRNA.
DR EMBL; HM769341; AEE25912.1; -; Genomic_DNA.
DR EMBL; CM000836; KRH65715.1; -; Genomic_DNA.
DR RefSeq; NP_001239777.1; NM_001252848.1.
DR AlphaFoldDB; C6T7L5; -.
DR STRING; 3847.C6T7L5; -.
DR PaxDb; 3847-GLYMA03G07570-1; -.
DR EnsemblPlants; KRH65715; KRH65715; GLYMA_03G056700.
DR GeneID; 100799517; -.
DR Gramene; KRH65715; KRH65715; GLYMA_03G056700.
DR KEGG; gmx:100799517; -.
DR eggNOG; ENOG502QQQ2; Eukaryota.
DR HOGENOM; CLU_033094_1_0_1; -.
DR InParanoid; C6T7L5; -.
DR OMA; KDHYVND; -.
DR OrthoDB; 4215at2759; -.
DR Proteomes; UP000008827; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042389; F:omega-3 fatty acid desaturase activity; IBA:GO_Central.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IBA:GO_Central.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 129..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..142
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 149..404
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
FT REGION 74..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 51350 MW; F5A7684DB0F310B8 CRC64;
MATWVLSECG LRPLPPVFPR STRPISCQKP SKSRFLSTNK GVPDLNLQAR GLTCCSFRDR
KWELGVSAPL KFATNEGEEE ERTNGANNGV GEEVSEFDPS APPPFKLADI RAAIPKHCWV
KDPWKSMSYV VRDVIVVFGL AAAAAYLNNW VVWPLYWAAQ GTMFWALFVL GHDCGHGSFS
NNPKLNSVAG HLLHSSILVP YHGWRISHRT HHQNHGHVEN DESWHPLPEK IFKSLDNVTR
ILRFTLPFPL LAYPIYLWSR SPGKTGSHFN PDSDLFVPSE RKDVITSTIC WTAMAALLVG
LGFVMGPVQL LKLYGIPYAI FVMWLDLVTY LHHHGHEDKL PWYRGEEWSY LRGGLTTIDR
DYGWINNIHH DIGTHVIHHL FPQIPHYHLI EATEAAKPVL GQYYREPKKS SPLPIYLIGE
LLRSMKKDHF VSDSGDIVYY QTDPTLSSSS TSQ
//
