ID C6WB22_ACTMD Unreviewed; 136 AA.
AC C6WB22;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Glyoxalase/bleomycin resistance protein/dioxygenase {ECO:0000313|EMBL:ACU39313.1};
GN OrderedLocusNames=Amir_5495 {ECO:0000313|EMBL:ACU39313.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU39313.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU39313.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
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DR EMBL; CP001630; ACU39313.1; -; Genomic_DNA.
DR RefSeq; WP_015804198.1; NC_013093.1.
DR AlphaFoldDB; C6WB22; -.
DR STRING; 446462.Amir_5495; -.
DR KEGG; ami:Amir_5495; -.
DR eggNOG; COG0346; Bacteria.
DR HOGENOM; CLU_046006_10_0_11; -.
DR OrthoDB; 9794917at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0004462; F:lactoylglutathione lyase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd07263; VOC_like; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 1.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR018146; Glyoxalase_1_CS.
DR InterPro; IPR037523; VOC.
DR PANTHER; PTHR36437; GLYOXALASE/BLEOMYCIN RESISTANCE PROTEIN/DIOXYGENASE; 1.
DR PANTHER; PTHR36437:SF2; GLYOXALASE_BLEOMYCIN RESISTANCE PROTEIN_DIOXYGENASE; 1.
DR Pfam; PF00903; Glyoxalase; 1.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR PROSITE; PS00934; GLYOXALASE_I_1; 1.
DR PROSITE; PS51819; VOC; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000313|EMBL:ACU39313.1};
KW Oxidoreductase {ECO:0000313|EMBL:ACU39313.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 4..133
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 136 AA; 15042 MW; 0E9D93915D722FE7 CRC64;
MNIRVSHTFL QVDDHDAALG FYRDTLGLEV RSDVSFNEFR WLSLGSSEQP GLEIVLESAD
MGRSPEDAKA INELRAKGSL SGLIFWVEDC DALFEKVRAS GAEVVQEPTD QDYGVRDCAF
RDPAGNQIRF SGKPAS
//
